Dr Horrible

You are all aware of Joss Whedon’s new mini-epic, Dr. Horrible’s Sing-Along Blog, I’m sure. If not, get over there now…it’s only freely available until Sunday night.

All I can say is that it is about time someone made a sympathetic, musical tribute to supervillains. Now I’m wondering, though…the ending is not satisfactory. I want more. Whedon cannot simply stop here with a single 3 part event. I want a weekly series on the internet!

I guess that means we should actually pay for these episodes, as encouragement.

Oh, and if you liked Felicia Day in Dr Horrible, check out The Guild.

Altenberg 2008 is over

Massimo Pigliucci has posted the notes, parts 1, 2, and 3, from the Altenberg meeting that was unfortunately over-hyped by the creationist crowd (no blame for that attaches to the organizers of this meeting). It sounds like it was a phenomenally interesting meeting that was full of interesting ideas, but from these notes, it was also clearly a rather speculative meeting — not one that was trying to consolidate a body of solid observations into a coherent explanation, but one that was instead trying to define promising directions for an expansion of evolutionary theory. That’s also the message of the concluding statement of the meeting.

A group of 16 evolutionary biologists and philosophers of science convened at the Konrad Lorenz Institute for Evolution and Cognition Research in Altenberg (Austria) on July 11-13 to discuss the current status of evolutionary theory, and in particular a series of exciting empirical and conceptual advances that have marked the field in recent times.

The new information includes findings from the continuing molecular biology revolution, as well as a large body of empirical knowledge on genetic variation in natural populations, phenotypic plasticity, phylogenetics, species-level stasis and punctuational evolution, and developmental biology, among others.

The new concepts include (but are not limited to): evolvability, developmental plasticity, phenotypic and genetic accommodation, punctuated evolution, phenotypic innovation, facilitated variation, epigenetic inheritance, and multi-level selection.

By incorporating these new results and insights into our understanding of evolution, we believe that the explanatory power of evolutionary theory is greatly expanded within biology and beyond. As is the nature of science, some of the new ideas will stand the test of time, while others will be significantly modified. Nonetheless, there is much justified excitement in evolutionary biology these days. This is a propitious time to engage the scientific community in a vast interdisciplinary effort to further our understanding of how life evolves.

That’s a little soft — there are no grand reformulations of the neo-Darwinian synthesis in there, nor is anyone proposing to overturn our understanding of evolution — but that’s what I expected. It’s saying that there are a lot of exciting ideas and new observations that increase our understanding of the power of evolution, and promise to lead research in interesting new directions.

Unfortunately, one reporter has produced an abominably muddled, utterly worthless and uninformed account of the Altenberg meeting that has been picked up by many crackpots to suggest that evolution is in trouble. This not only ignores a fundamental property of science — that it is always pushing off in new directions — but embarrassingly overinflates the importance of this one meeting. This was a gathering of established scientists with some new proposals. It was not a meeting of the central directorate of the Darwinist cabal to formulate new dogma.

Where one ignorant kook dares to assert her inanity, you know the Discovery Institute will stampede after her. Both Paul Nelson and now Casey Luskin have cited her lunatic distortions favorably. Luskin’s account is egregiously incompetent, as we’ve come to expect — he even thinks Stuart Pivar was an attendee. Pivar is an eccentric New York art collector, heir to a septic tank fortune, who has no training in science and whose “theory” is a nonsensical bit of guesswork that is contradicted by observations anyone can make in a basic developmental biology lab. He was not at the meeting. No one in their right mind would even consider inviting him to such a serious event. Maybe if it was a birthday party and they needed someone to make balloon animals, he’d be a good man to have on hand.

Now we can move beyond the garbled hype of the creationists. Pigliucci lists several concepts up there that have promise for further research, and that may help us understand evolution better. That’s the productive result of the meeting, and the only part that counts. Those concepts are also going to be discussed by many other scientists at many other meetings — even I talked about some of them recently — but don’t let the liars on the creationist side confuse you into thinking that the fact that scientists are talking about new ideas is a sign that evolution is in crisis. Talking about new ideas is normal science.

Pathological cephalopod

Teratology is so interesting — it gives us hints about the mechanisms driving developmental processes. In some cases, when you just have a few isolated instances, it can be frustrating, because there isn’t enough information to go much beyond speculation. Here’s one of those tantalizing cases: an octopus with branching tentacles.

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Now that is fascinating. Look at limb formation as an abstract developmental problem in which you first have to initiate a protrusion from a specific place on the body wall; the protrusion has to elongate to a specific length; and it has to be patterned along its length. Cephalopod limb patterning doesn’t involve any branching elements, unlike vertebrate limbs which show a limited radiation of bony elements as you go distally. Vertebrates can exhibit phenomena like polydactyly which are basically counting errors or expansions of a field; the mechanisms for that don’t seem likely to be the case in cephalopods. What I’d guess is that this is an example of errors in initiation. Whatever the signal is that triggers limb extension from the body was triggered again and again as the arm grew, creating sub-arms and sub-sub-arms. This could be a consequence of a mutation that lifted normal constraints that pattern limb initiation (this animal lived for some time, and produced offspring with normal limbs, all of which died shortly after hatching, unfortunately, a result that is ambiguous in determining whether the problem is genetic), or it could be an environmental signal that mimics the normal developmental signal. You can’t tell from one dead octopus!

It’s still cool, though, and says we need more research on cephalopod development.

Netroots Nation

I’m a little bit jealous: Seed is well represented at Netroots Nation, but I couldn’t swing it this year. It’s just as well, as it would have been sandwiched in between a couple of other jaunts, and I’m still trying to get back on my feet after wearing myself out in Atlanta.

It would have been great, though — a group of us, including me and Michael Bérubé, had a proposed session on academic freedom/”academic bill of rights” that got turned down. If you’re there, tell the organizers to bring us on next year!

I don’t think this is the message he wanted me to come away with

Christianity is like sticking a fork in your face and your rectum and plugging them into a wall socket. Your insides will smoke and sizzle, you’ll glow, sparks will shoot out of you, and you’ll become a cooked vegetable.

At the end, he says, “don’t try to do this at home, because it can be very dangerous”. That’s the honest part of his example. Kids, don’t do religion! It’s very, very bad for you!

Someone was awake at GECCO

Hooray, I have evidence that at least one person didn’t fall asleep at my GECCO keynote: here’s a summary. He even managed to pay attention right up to the dramatic conclusion, which I usually keep a secret, but now the beans have been spilled.

Wait…the biology-oriented keynote at last year’s GECCO was a panel with Lewis Wolpert, Steve Jones, and Richard Dawkins? I would have been a lot more nervous if I’d known I was following up that act.

I guess this shouldn’t be surprising

The Republican National Convention is being held in St Paul at the Xcel Energy Center. My fellow Minnesotans are familiar with this place — it’s right across the street from the Science Museum of Minnesota. Would you believe the science museum is being closed to the public during the convention? There’s a metaphor jumping up and down, screaming for attention in that.

You know, shutting down the museum is probably a more effective way of discouraging me from frightening the Republicans than posting more armed guards, as Thomas Foley wants to do.