Evolutionary gems

This week, Nature magazine published a short list of recent important developments in evolutionary biology that support the theory of evolution, as a tool to help explain that evolution is definitely a dynamic and useful theory in our field and to demonstrate that the evidence is still growing. Here’s a short summary of the 15 stories the editors picked out, but you should also read the freely available article, 15 Evolutionary Gems. Teachers, put this in your classroom!

  1. The discovery of Indohyus, an ancestor to whales.

  2. The discovery of Tiktaalik, an ancestor to tetrapods.

  3. The origin of feathers revealed in creatures like Epidexipteryx.

  4. The evolution of patterning mechanisms in teeth.

  5. The developmental and evolutionary origin of the vertebrate skeleton.

  6. Speciation driven indirectly by selection in sticklebacks.

  7. Selection for longer-legged lizards in Caribbean island populations.

  8. A co-evolutionary arms race between Daphnia and its parasites.

  9. Non-random dispersal and gene flow in populations of great tits.

  10. Maintenance of polymorphisms in populations of guppies.

  11. Contingency in the evolution of pharyngeal jaws in the moray.

  12. Developmental genes that regulate the shape of beaks in Darwin’s finches.

  13. Evolution of regulatory genes that specify wing spots in Drosophila.

  14. Evolution of toxin resistance.

  15. The concept of evolutionary capacitance: the idea that environmental stress can expose hidden variations that are then subject to selection.

Machines of aggressively loving grace

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Squid don’t just make sperm: they package it up into fairly elaborate little torpedoes called spermatophores, which are either handed to the female with a specially modified arm called the hectocotyl arm, or squirted onto her with a penis. Once on the female (or a male, it really doesn’t matter), the spermatophore everts, forming a structure called the spermatangia, in which all the packed sperm uncoil, ready to do their job, and the whole mass is anchored to the target with a cement body. These structures do show species-specific differences, but here is one example from Heteroteuthis dispar.

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Heteroteuthis dispar. Spermatophore (a) and spermatangium (b)

Now the curious observation: squid are often captured festooned with spermatophores and spermatangia, and in many cases, the spermatangia may be imbedded deeply into the musculature of the animal — so it’s not simply as if the spermatophores are lovingly placed in an appropriate orifice, they are piercing the female (or the male, again, they don’t care that much), tearing deep into the interior. The question is, how do they get in there?

A few simple observations have revealed the answer. Spermatophores can be triggered by a gentle squeeze, at which time all of their fertilization machinery will fire. Here are some photos of some spermatophores going to work on a squid carcass.

i-cfa7b64f89849ec640df781a4b43dd43-implant.jpeg(A) Placement of spermatophores on a dead male specimen of Moroteuthis ingens (mantle length ~300
mm) and initiation of the spermatophoric reaction by pressing on the ejaculatory apparatus with a forceps. (B)
Same specimen, but submerged in seawater, showing the ejaculating spermatophores. (C) Exterior view of
implanted spermatangia in tissue of a female, showing the site of penetration and part of the amber ejaculatory
apparatus. (D) Interior view of same spermatangia, showing the sperm mass and the amber ejaculatory apparatus.

(Read the caption carefully. That’s a human triggering sperm to ejaculate into a dead male squid. It’s gay necrophiliac bestiality! You don’t see that in the papers every day.)

The answer is that spermatophores also release digestive enzymes and actively burrow into the target tissue. Squid sperm show an aggressive persistence and vigorously active assault on the female body that our own pathetic human emissions lack…I feel a little inadequate, but I’m sure women are a bit relieved.

Another interesting observation is the function of the squid penis. It seems to be less an intromittent organ than a kind of hose to direct the ejaculations onto the female. In natural situations, unlike the photographs above, it is responsible for initiating the spermatophore reaction. Each spermatophore has a threadlike extension of a surrounding membrane, and tugging on that triggers the reaction. It’s like a squad of paratroopers leaping out of a phallic airplane, each attached by a static line that yanks the rip cord as they emerge.

Hoving HJT, Laptikhovsky V (2007) Getting under the skin: autonomous implantation of squid spermatophores. Biological Bulletin 212: 177-179.

Soon, we’ll be reading your minds!

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No, not really, but this is still a cool result: investigators have used an MRI to read images off the visual cortex. They presented subjects with some simple symbols and letters, scanned their brains, and read off the image from the data — and it was even legible! Here are some examples of, first, the images presented to the subjects, then a set of individual patterns from the cortex read in single measurements, and then, finally, the average of the single scans. I think you can all read the word “neuron” in there.

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Reconstructed visual images. The reconstruction results of all trials for two subjects are shown with the presented images from the figure image session. The
reconstructed images are sorted in ascending order of the mean square error. For the purpose of illustration, each patch is depicted by a homogeneous square,
whose intensity represents the contrast of the checkerboard pattern. Each reconstructed image was produced from the data of a single trial, and no postprocessing was applied. The mean images of the reconstructed images are presented at the bottom row. The same images of the alphabet letter ”n” are displayed in
the rightmost and leftmost columns.

Before you get all panicky and worry that now the CIA will be able to extract all of those sexy librarian fantasies out of your brain by aiming a gadet at your head, relax. This is an interesting piece of work, but it has some serious limitations.

  • This only works because they are scanning the part of the visual cortex that exhibits retinotopy — a direct mapping of the spatial arrangement of the retina (and thus, of any images falling on it) onto a patch of the brain at the back of your head. This won’t work for just about any other modality, except probably touch, and I doubt it will work for visualization/cognition/memory, which are all much more derived and much more complexly stored. Although I’d really like to know if someone closes their eyes and merely imagines a letter “E”, for instance, whether there isn’t some activation of the visual cortex.

  • The process was time consuming. Subjects were first recorded while staring at random noise for 6 seconds in 22 trials. This was necessary to get an image of the background noise of the brain, wwhich was subtracted from subsequent image measurements. The brain is a noisy place, and the letter pattern is superimposed on a lot of background variation. Then, finally, the subject has to fixate on the test image for 12 seconds.

  • Lastly, a fair amount of math has to be flung at the scan to extract the contrast information. This is probably the least of the obstacles, since computational power seems to increase fairly rapidly.

Give this research some more time, though, and I can imagine some uses for being able to record specific aspects of brain states. I’d be more interested in a device that can read pre-motor cortex though — I’d like to get rid of this clumsy keyboard someday.

Miyawaki Y, Uchida H, Yamashita O, Sato M-a, Morito Y, Tanabe HC, Sadato N, Kamitani Y (2008) Visual Image Reconstruction from Human Brain Activity using a Combination of Multiscale Local Image Decoder. Neuron 60(5):915-929.

Amylase and human evolution

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I made a mistake that was quickly corrected by a correspondent. Yesterday, in writing about copy number variants in human genes, I used the example of the amylase gene on chromosome 1, which exists in variable numbers of copies in human populations, and my offhand remark was that the effect is “nothing that we can detect”, but that maybe people with extra copies would be “especially good at breaking down french fries”. Well, it turns out that we can detect this, that there was even a very cool study of this enzyme published last year, and that the ability to break down complex starches rapidly may have been a significant factor in human evolution.

So of course I have to tell you all about this now.

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Copy Number Variants are not evidence of design

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The Institute for Creation Research has a charming little magazine called “Acts & Facts” that prints examples of their “research” — which usually means misreading some scientific paper and distorting it to make a fallacious case for a literal interpretation of the bible. Here’s a classic example: Chimps and People Show ‘Architectural’ Genetic Design, by Brian Thomas, M.S. (Note: this is not the peer-reviewed research paper implied by the logo to the left — that comes later.) The paper is a weird gloss on recent work on CNVs, or copy number variants. Mr Thomas makes a standard creationist inference that I have to hold up for public ridicule.

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A Natural History of Seeing: The Art and Science of Vision

Simon Ings has written a wonderful survey of the eye, called A Natural History of Seeing: The Art and Science of Vision(amzn/b&n/abe/pwll), and it’s another of those books you ought to be sticking on your Christmas lists right now. The title give you an idea of its content. It’s a “natural history”, so don’t expect some dry exposition on deep details, but instead look forward to a light and readable exploration of the many facets of vision.

There is a discussion of the evolution of eyes, of course, but the topics are wide-ranging — Ings covers optics, chemistry, physiology, optical illusions, decapitated heads, Edgar Rice Burroughs’ many-legged, compound-eyed apts, pointillisme, cephalopods (how could he not?), scurvy, phacopids, Purkinje shifts…you get the idea. It’s a hodge-podge, a little bit of everything, a fascinating cabinet of curiousities where every door opened reveals some peculiar variant of an eye.

Don’t think it’s lacking in science, though, or is entirely superficial. This is a book that asks the good questions: how do we know what we know? Each topic is addressed by digging deep to see how scientists came to their conclusion, and often that means we get an entertaining story from history or philosophy or the lab. Explaining the evolution of our theories of vision, for example, leads to the story of Abu’Ali al-Hasan ibn al-Hasan ibn al-Haythem, who pretended to be mad to avoid the cruelty of a despotic Caliph, and who spent 12 years in a darkened house doing experiments in optics (perhaps calling him “mad” really wasn’t much of a stretch), and emerged at the death of the tyrant with an understanding of refraction and a good theory of optics that involved light, instead of mysterious vision rays emerging from an eye. Ings is also a novelist, and it shows — these are stories that inform and lead to a deeper understanding.

If the book has any shortcoming, though, it is that some subjects are barely touched upon. Signal transduction and molecular evolution are given short shrift, for example, but then, if every sub-discipline were given the depth given to basic optics, this book would be unmanageably immense. Enjoy it for what it is: a literate exploration of the major questions people have asked about eyes and vision for the last few thousand years.

The radiation of deep sea octopuses

Last week’s Friday Cephalopod actually has an interesting story behind it. It was taken from a paper that describes the evolutionary radiation of deep-sea cephalopods.

First, a little background in geological history. Antarctica is a special case, in which a major shift in its climate occurred in the last 50 million years. If you look at a map, you’ll notice that Antarctica comes very close to the southern tip of South America; 50 million years ago, they were fully connected, and they only separated relatively recently due to continental drift.

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An audio advent calendar

The New Humanist blog is running an advent calendar podcast, in which various people are asked what scientist they’d like to have a Christmas-style celebration around, and what invention from scientific history they’d most like to receive for Christmas.

First up is Stephen Fry, who made the interesting choice of Robert Hooke — I approve, he’s an interesting character — and all he wants for Christmas is an orrery.

You’ll have to listen every day. I’m going to be in there somewhere, and Richard Dawkins gets to be the Christmas eve fairy.

Interpretive dance, really?

Whoa. It’s kind of a standing joke that when our presentation tools fail us, we’ll have to fall back on interpretive dance to make our points. We never mean it seriously, though. Until now. Science magazine challenged researchers to actually illustrate their work with dance, and people did! There are four youtube videos at that link that show the winners. I liked the graduate student entry best, but I’ll include this one because a) it was most comprehensible to me, and b) Laurie Anderson is wonderful.

You will never catch me doing this, though — I can’t dance, and I’m too ungainly anyway.

Odontochelys, a transitional turtle

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Now this is an interesting beast. It’s a 220 million year old fossil from China of an animal that is distinctly turtle-like. Here’s a look at its dorsal side:

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a, Skeleton in dorsal view. b, Skull in dorsal view. c, Skull in ventral view. d, Body in dorsal view. Teeth on the upper jaw and palatal elements were scratched out during excavation. Abbreviations: ar, articular; as, astragalus; ca, calcaneum; d, dentary; dep, dorsal process of epiplastron; dsc, dorsal process of scapula; ep, epiplastron; fe, femur; fi, fibula; gpep, gular projection of epiplastron; hu, humerus; hyo, hyoplastron; hyp, hypoplastron; il, ilium; ipt, interpterygoid vacuity; j, jugal; ldv, last dorsal vertebra; m, maxilla; n, nasal; na, naris; op, opisthotic; p, parietal; phyis, posterolateral process of hypoischium; pm, premaxilla; po, postorbital; prf, prefrontal; q, quadrate; sq, squamosal; st, supratemporal; sv1, 1st sacral vertebra; ti, tibia; ul, ulna; vot, vomerine teeth; I, V, 1st and 5th metatarsals.

Notice in the skull: it’s got teeth, not just a beak like modern turtles. The back is also odd, for a turtle. The ribs are flattened and broadened, but…no shell! It’s a turtle without a shell!

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