Ontogenetic depth

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One of the serious shortcomings of Intelligent Design is that it does nothing to provide any new or productive insights into the workings of biology. ID proponents seem to be at least vaguely aware of this failure, in that they do frequently claim to be thinking about working on a preliminary, tentative approach towards the beginnings of a potential research program (my paraphrase), but most of the effort has been directed towards political and legal enforcement of their ideas, rather than actually testing those ideas. One advantage of pursuing only legalisms is that they don’t give scientists anything to grapple. Invariably, when ID proponents do dip their toes in the scientific waters, they end up getting eaten by the sharks that lurk there.

One example: Paul Nelson, of the Discovery Institute, has been peddling a peculiar idea he calls “ontogenetic depth” as a scientific concept that emerges from Intelligent Design. To his credit, he has been presenting this idea in legitimate science venues, at the Geological Society of America and Society for Developmental Biology meetings. Note that getting on the program at these meetings is not subject to peer-review, so it is not automatically a recognition of merit that this work has been presented publicly. It is a good sign that Nelson is willing to expose his work to criticism, though.

I’m going to give it some criticism here. “Ontogenetic depth” is a developmental idea, and I’m a developmental biologist. Today I also get to play shark.

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The Sunday morning session at the Oregon evo-devo symposium

[Since I had to fly away early this morning and missed all these talks, I had to rely on regular commenter DanioPhD to fill in the gaps … so here’s her summary:]

This morning’s final series of talks each focused on a different phylum, but the unifying theme was one of bridging the processes of microevolution and macroevolution. The first talk after breakfast (and a long night of Scotch-drinkin’ and story-swappin’ prior to that) was Bernie Degnan of the University of Queensland. He summarized his work on Amphimedon queenslandica, a sponge species developed as a model of a representative primitive metazoan. Sponges diverged from the metazoan lineage ca. 700 MYA and possess the most minimalist metazoan body plan–no nervous system, muscles, nor any discernible tissues in the adult body architecture. Their embryos, however, feature robust anterioposterior patterning, distinct cell types organized into tissues, and cell morphogenesis typical of more complex metazoans. These embryonic characteristics are achieved by a regulatory network of genes, which, while inactive in the adult sponge, strongly support the presence of similar molecules in the ancestral metazoan genome. A few million years after the divergence of porifera, metazoans were able to co-opt these molecular toolkits to build the diverse, molecularly and morphologically distinct tissues common to all bilaterians. PZ has previously written up one such sponge tale here describing the molecular precursors to a nervous system in the sponge genome. Precursors to pretty much every other developmental ‘big gun’, e.g, Hox genes, Pax genes, Wnts, Hedgehog, etc. are also present as a basic prototype, in the Amphimedon genome.

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Dragooned and disgusted

You know, I caught a plane at 5:20am this morning, had a long flight across the country followed by a 3 hour drive to get home, so I’m not exactly feeling pleasantly conducive to continuing the latest sanctimonious whine-fests from some of the people who share a server with me. I have been avoiding the various framing flare-ups around here, despite the fact that everyone of them seems to drag my name into the mix.

We appreciate your concern, it is noted and stupid.

I will defer to Greg and Russell and let them speak for me, since at this point, I really don’t give a damn about the issue. I will say this: if you think your role is to hector me about being someone else, you’re a clueless twit.

I am not Paul Kurtz. I am not Eugenie Scott. I am not Richard Dawkins. I am not your wonderful third grade teacher or the boy scout who helps little old ladies across the street, and I am not Jesus nor am I Satan. I’m me, and no one else, and I expect everyone else to be themselves. I am not practicing “identity politics”, since the only identity I have is my individuality and if there’s anything I want everyone to do it is to be able to be fierce and outspoken and say what they think. Or, as some of you obviously prefer, you can be as tepid and craven and milquetoastish as you want, and you can set your stars on being someone else and inoffensively following the crowd to your heart’s content.

But get over yourselves. That’s not my road, and I’m not following your directions, especially when they’re so goddamned boring and derivative.

A few random thoughts as I head back home

  • It was nothing but gray skies and intermittent rain while I was there. It was so beautiful … it felt like home. It was also good seeing my old mentors from grad school days, Chuck Kimmel and John Postlethwait.

  • Patrick Phillips played this video on the big screen. In my presence. I thought about hiding under a table.

  • The wackaloons of the Oregon Right to Life group were meeting in the same hotel with us. They should have snuck into our talks and seen all the pretty embryos we were looking at. Or maybe some of us should have snuck into their sessions, so there’d be at least a few people in the room who know something about embryology.

  • It was a fairly small meeting, about 100 people. That’s the way I like them — I actually got to meet some new faces.

  • The most horrifying story: Jerry Coyne mentioned that people had written in to say that Hopi Hoekstra did not deserve tenure after publication of the now infamous Hoekstra and Coyne paper, which was critical of evo-devo. That was unbelievable. I didn’t agree with everything in the paper, but then 1) I don’t agree with everything in any paper, and 2) it was useful, productive criticism.

  • I really like this IGERT program. Sometimes, the granting agencies get a great idea.

  • I am very, very tired, but it’s a good tired.

The afternoon session at the Oregon evo-devo symposium

I’m going to get off a quick summary of this afternoon’s talks, then I have to run down to the poster session to find out what the grad students have been doing. Are we having fun yet? I’m going to collapse in bed tonight, and then unfortunately I have to catch an early flight back home, so I’m going to miss a lot of cool stuff tomorrow.

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The morning session at the Oregon evo-devo symposium

My brain is most wonderfully agitated, which is the good thing about going to these meetings. Scientists are perverse information junkies who love to get jarred by new ideas and strong arguments, and meetings like this are intense and challenging. I’ve only got a little time here before the next session, so let me rip through a short summary of my morning.

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