Modules and the promise of the evo-devo research program

Since Evolgen recognizes the importance of evo-devo, I’ll return the favor: bioinformatics is going to be critical to the evo-devo research program, which to date has emphasized the “devo” part with much work on model systems, but is going to put increasing demands on comparative molecular information from genomics and bioinformatics to fulfill the promise of the “evo” part. I’m sitting on a plane flying east, and to pass the time I’ve been reading a very nice review of the concept of modularity in evo-devo by Paula Mabee (also a fish developmental biologist, and also working in a small college in a small town in the midwest…but rather deservedly better known than yours truly). In addition to summarizing the importance of the concept of modularity to evolution and development, the paper also does something I always appreciate: it summarizes the key questions that the modern evo-devo research program is working to answer.

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Our trip so far

We were supposed to arrive in NYC at 2, this afternoon.

The plane was diverted because La Guardia was socked in with storms. We spent the afternoon sitting on a runway in Allentown, Pennsylvania. An hour passed. Another, and another, and another. We got vague promises over the intercom, always saying our departure was sometime in the near future. We stopped believing the captain in the early evening.

We had just killed the fat one, the one whose glasses we used to start the bonfire in first class, the one we called “Piggy,” when the captain came on again and told us to fasten our seat belts and be sure our carry-ons were stowed. Woo-heee, were we ever abashed.

We put our shirts and pants back on and finally landed in the Big City around about 8.

Plans, plans, plans

You may be thinking that Pharyngula is going to be awfully quiet this weekend, what with the proprietor gallivanting off to that liberal hotbed of iniquity, New York City. Well, yeah, I probably am going to be rather busy, but I think I’ll be able to squeeze in a few things, especially since this tendinitis I’ve got is going to restrict my mobility a bit. Also, if any New Yorkers want to meet up, my schedule is little bit tight, but I might be reachable at a few times. I’m staying at the Grand Hyatt New York, Park Avenue at Grand Central Station, at (212) 883-1234. Late Saturday morning I’ll be at the AMNH (of course!) touring the Darwin exhibit, and that evening at 8 we’re going to be on Broadway, attending a musical…but late afternoon and early evening are free. I’m also probably going to be hobbling about the Bronx Zoo on Sunday, before my plane whisks me back to the desolate plains of Minnesota.

Guarded outrage, with intimations of futility

Do I believe that George W. Bush stole the last election and that the Republican party is run by criminals and traitors? You betcha. With his record of sloppy analysis, though, I just wish someone more trustworthy than Robert F. Kennedy, Jr. had authored that report.

I also don’t see much in the way of productive suggestions about what to do to prevent it from happening again. If Republican operatives are in a position to commit such sweeping acts of anti-Democratic corruption, what’s to prevent it from happening again this fall? What are we going to do if it does happen again?

Two flat tires

My day has not been off to a good start. I’m supposed to fly off to New York tomorrow morning, and just to inspire worry in me, my car had a flat this morning. When just getting to the airport is a three-hour drive, hints of unreliability in the vehicle are not reassuring.

Worse still, I’m having a flare-up of Achilles tendinitis. Every step sends piercing pains shooting up my leg, and unfortunately I know from past experience that not continuing some gentle stretching and exercise will lead to my whole ankle seizing up and rendering me immobile. So, I’m going to be hobbling about New York City in pain this weekend. If any of you New Yorkers notice a guy who reminds you of that irascible gimp, House—only shorter and pudgier—that’s me.