How octopus suckers work

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Whoa, it’s been a while since I’ve said anything about my infatuation with cephalopods (since, like, the last post…). Let’s correct that with a nifty paper I found on octopus suckers.

Here’s a typical view of a tangle of octopus arms, all covered with circular suckers. The octopus can cling to things, grasp prey and other objects with those nifty little discs, and just generally populate people’s nightmares with the idea of all those grappling, clutching, leech-like appendages.

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Beautiful birds?

Crap. Coturnix tagged me with this beautiful bird meme, and I am the wrong person to ask. I don’t get out much, preferring to sit in the lab or the library, so my favorite birds are all in pieces and dead. But OK, since he asked…

A complex regulatory network in a diploblast

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The Wnt genes produce signalling proteins that play important roles in early development, regulating cell proliferation, differentiation and migration. It’s hugely important, used in everything from early axis specification in the embryo to fine-tuning axon pathfinding in the nervous system. The way they work is that the Wnt proteins are secreted by cells, and they then bind to receptors on other cells (one receptor is named Frizzled, and others are LRP-5 and 6), which then, by a chain of cytoplasmic signalling events, removes β-catenin from a degradation pathway and promotes its import into the nucleus, where it can modify patterns of gene expression. This cascade can also interact with the cytoskeleton and trigger changes in cell migration and cell adhesion. The diagram below illustrates the molecular aspects of its function.

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