Covid-19 fatigue

I am one of the fortunate ones in that I was able to get vaccinated and boosted and since I am retired, during the worst of the pandemic I could spend most of my time at home and thus could easily practice social distancing. I also wore masks whenever I was in any indoor facility with other people. But while it was not onerous, I too have started to feel weary of taking these precautions and was hopeful that the rapid decline in cases in the recent past signaled the transition from a pandemic phase to an endemic phase that would enable us to let down our guard and just take the kinds of precautions we are used to with other familiar airborne contagions like the flu and cold, where we stay at home when we have symptoms and avoid contact with people who are exhibiting symptoms.

But now we hear reports of a delta-omicron hybrid and a BA.2 version of the omicron variant causing a slight uptick in cases in Europe and the UK, which in the past have been leading indicators of what would happen in the US after about two or three weeks. 45% of the US population has been infected with omicron and thus have some immunity to that BA.2 version of it but that still leaves a large number at risk.
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A set of podcasts worth browsing

A friend alerted me to the existence of this series of fascinating BBC podcasts called In Our Time. Each 40-50 minute episode consists of the host Melvin Bragg exploring one topic in depth with three academics from various British universities and research institutions. Originating in 1998, it produces a new episode each week and by now its archives have close to 1,000 podcasts. Each episode also has a comprehensive reading list for those who want to know more. The topics range all over the place, covering science, history, literature, art, religion, and so on so that anyone will find something that appeals to them or are curious about. Since the panelists are experts in the area being discussed, one gets reliable information based on in-depth research. The program is ideal for a generalist like me.
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Absolute and relative risk

Probability can be deceptive. The concept sounds easy to understand and we glibly use the ideas in everyday life but there are many subtleties involved. Given how important probabilistic ideas are in life, some have suggested that it be introduced into school mathematics curricula much earlier than it currently is and discussed in more depth.

One subtlety can be highlighted by this example. Suppose that you read about a new study that finds that by taking some measures, you can reduce the risk of stroke by 50%. Should you adopt those measures?

To make a decision you need to weigh the benefit against the costs, which in this case may be that the measures involve taking medications that have rather serious side effects, or that the regimen involved is arduous, or that it is very expensive. But even taking those into account is not enough to decide because you need to know another key piece of information and that is the absolute risk numbers.

The relative risk is what is usually reported and quoted in the media. It is obtained by comparing the results of the test group with the control group. So if the test group has five positive cases and the control group has ten, then the relative risk reduction is 50%. But this ignores the importance of sample size that determines the absolute risk. If the sample size had been 10,000, the absolute risk would have dropped from 0.1% to 0.05%.

Paula Byrne, one of the authors of a recent study on the benefits of taking statins to lower cholesterol, says that focusing only on relative risk does not give enough information to make an informed decision.
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One time all year round? I did not see that coming

As long time readers know, I grumble about that biannual ritual in the US of changing the clocks forward by one hour in the spring (when it becomes Daylight Savings Time) and then one hour back in the fall (when it reverts to Standard Time). We just made the change this past Sunday and I went around changing the eight clocks that are not connected to the internet. You would think that I would have been on top of this issue but I was taken completely by surprise to learn that the US Senate yesterday unanimously passed a resolution making DST permanent

That does not mean that the deed is done. The House of Representatives has not passed the measure and Joe Biden has not stated that he will sign the bill into law.
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What is so hard about the ‘hard problem’ of consciousness?

I am a materialist in the sense that I think that all phenomena arise due to material entities interacting according to laws of nature. I have seen no reason to think that anything supernatural or mystical is needed to be invoked to explain anything. I have sometimes been asked by people, usually the religious seeking to challenge my atheistic viewpoint that the material world is all there is and does not allow for any gods, as to how I can explain love. They seem to think that love is an immaterial quantity and that believing in its existence requires the same leap of faith as believing in a god. I reply that love is an emotion that is created by the workings of my brain that releases certain substances that cause me to have that feeling I point out that when I die, any love that I feel for anyone or anything will die with me. It does not survive the death of my brain.
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Paul Farmer has died

I read the tragic news of his death at the young age of 62 in Rwanda. Farmer was one of the truly inspiring people. A highly trained doctor who came from humble beginnings, his mission in life was to bring high quality health care to some of the poorest nations in the world, starting with Haiti. A strong believer in the need for global justice and equity, along with Ophelia Dahl (who happens to be the daughter of children’s author Roald Dahl and Academy Award winning actress Patricia Neal), he co-founded the organization Partners in Health which I have supported for many years. They sent me an email announcing the sad news and saying that his death was due to an ‘acute cardiac event’, which I understand to be a heart attack. The Miami Herald has a report.

Dr. Paul Farmer, the renowned infectious disease specialist who devoted his life to fighting deadly epidemics and spent the last several years working on four continents delivering health care to millions, has died in Rwanda, his organization Partners in Health confirmed. He was 62.

A Florida native who lived in Miami with his wife and children when he wasn’t traveling or teaching at Harvard University, Farmer was co-founder of Partners In Health, a nonprofit health care organization based in Boston with a sister organization, Zanmi Lasante, in Haiti.

The recipient of many awards, one of his most recent being the 2020 Berggruen Prize for Philosophy and Culture, and its $1 million cash award, Farmer told the Miami Herald that his personal mission was to change the way humans think of infectious disease and address social inequalities in health care delivery.
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NFTs are a playground for crooks and grifters

NFT’s (Non-Fungible Tokens) are the new rage, riding the wave of the fascination with blockchain and cryptocurrency, two other things that do not seem to deter people from getting on the bandwagon even though they may have just the haziest idea of what they are. Naturally this leads to crooks moving in, selling NFTs of items that do not even belong to them.

When Lois van Baarle, a Dutch artist, scoured the biggest NFT marketplace for her name late last year, she found more than 100 pieces of her art for sale. None of them had been put up by her.

Van Baarle is a popular digital artist, with millions of followers on social media. She’s one of a growing number of artists who have had online images of their art stolen, minted as unique digital assets on a blockchain, and offered up to trade in cryptocurrency on the NFT platform OpenSea.
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