Lewis Wolpert has died

This is sad — Wolpert was one of my favorite developmental biologists. Years ago I wrestled with my choice of developmental textbook, between Scott Gilbert’s Developmental Biology, which is very very good, and Wolpert’s Principles of Development, which I eventually decided was a better fit to how I taught the course. I also appreciated his work on positional information and patterning. And now he has died at the age of 91, and only now do I find out that he lived an interesting life.

He studied civil engineering at the University of the Witwatersrand, where he became involved in progressive politics, helping to distribute communist literature in the townships; in 1952 he met Nelson Mandela. After two years working on soil mechanics as assistant to the director of the Building Research Institute in Pretoria, he hitchhiked to Europe, working briefly for the water planning board in Israel before studying soil mechanics at Imperial College London.

His life was changed when a friend in South Africa wrote to suggest he apply his knowledge of mechanics to the study of dividing cells. The biophysicist James Danielli at King’s College London accepted him as a PhD student, and with a Swedish colleague, Trygve Gustafson, he went on to measure the mechanical forces involved in cell division. He was promoted to lecturer and reader (in zoology) at King’s before taking up the chair of biology as applied to medicine at the Middlesex (transferred to University College London after the two institutions merged), where he remained until he retired aged 74.

He was also a great popularizer with a radio show discussing science in the UK, which I’ve had difficulty finding here — he does have a debate with William Lane Craig on YouTube, which I’ve avoided ever watching, because I can’t stand that sanctimonious Christian liar. Wolpert also has some things I disagree with, such as his gender essentialist leanings, a common problem with older developmental biologists steeped in model systems and lacking exposure to population thinking.

It wasn’t all an upward ascent for him. He suffered from a crippling depression.

The marriage to Elizabeth ended in divorce, and in 1993 Wolpert married the Australian writer Jill Neville. It was when his working and home lives were at their most secure and harmonious that a suicidal episode led to him spending three weeks in hospital. He recovered after treatment with antidepressants and cognitive behavioural therapy. Jill died suddenly of cancer in 1997.

Lately I’ve come to appreciate how devastating depression can be. And cancer sucks.

Do the COVIDiots even understand actuarial statistics?

Because I find this rather convincing that COVID-19 is much more than “just a flu”.

The Minnesota numbers are in, and they don’t look good.

Minnesota suffered more than 50,000 deaths in a year for the first time in recorded state history in 2020, mostly because of COVID-19 but also due to rising drug abuse and worsening racial health disparities.

A 15% increase in mortality from 2019 to 2020 demonstrates that the pandemic actually caused more deaths in Minnesota and wasn’t just a substitute cause for people who were likely to die anyway.

Hey, can we simplify that and just call all the deaths due to the neglected pandemic response, the erosion of our social safety net, and racism the Republican death toll?

Could MegaFarmCorps do good for the land?

Every Fall, as I travel around, I’m mystified by all the freshly harvested fields, black with exposed soil, and I wonder…isn’t that a bad idea? Isn’t that nice rich dirt going to wash away when the snow melts and the spring rains arrive? But what do I know? I’m not a farmer. I never studied agriculture, so I’m just going to trust the experts whose livelihood depends on their land.

Of course, my confidence tends to be eroded by all the Trump signs on those fields.

But good news! For once, the giant food corporations are trying to do something for the environment. They’re giving farmers incentives to practice something called regenerative agriculture.

Still, the companies’ moves have the potential to expand the use of unconventional farming practices known as regenerative agriculture. The movement represents a fundamental change to the way mainstream farmers manage their fields.

Regenerative principles call for reducing or even eliminating such mainstays of farming as tilling the soil before sowing seeds. Other regenerative techniques include planting cover crops, so soil is never bare; expanding plant diversity; adding livestock to an operation; and reducing or eliminating the use of chemicals.

The system has benefits such as storing more climate-altering carbon in the soil, improving water quality by preventing runoff, and reducing the need for pesticides by increasing insect biodiversity. Research shows it can also make farms more profitable by reducing the cost of chemicals and fertilizer and spreading price risk among many crops instead of just corn and soybeans.

“It’s not just about carbon. It’s not just a water benefit,” Sirolli said. “You get all of these different benefits that you stack together that benefit the community, that benefit the planet, while at the same time making sense for the farmer.”

See? I am learning something about farming. Although to be fair, if I’d been asked, I would have made suggestions along those same lines, although having to be admittedly vague about how to implement them.

I was probably thinking selfishly, though. Fewer pesticides → more plant and insect diversity → MORE SPIDERS. Also all those agricultural pollutants are just bad for us.

Overall, the Minnesota River is unhealthy. Sediment clouds the water, phosphorus causes algae, nitrogen poses risks to humans and fish, and bacteria make the water unsafe for swimming.

There are going to be so many wild books out of the last administration

Wow. You just have to read this account of a last ditch desperate meeting in the White House.

Four conspiracy theorists marched into the Oval Office. It was early evening on Friday, Dec. 18 — more than a month after the election had been declared for Joe Biden, and four days after the Electoral College met in every state to make it official.

“How the hell did Sidney get in the building?” White House senior adviser Eric Herschmann grumbled from the outer Oval Office as Sidney Powell and her entourage strutted by to visit the president.

President Trump’s private schedule hadn’t included appointments for Powell or the others: former national security adviser Michael Flynn, former Overstock.com CEO Patrick Byrne, and a little-known former Trump administration official, Emily Newman. But they’d come to convince Trump that he had the power to take extreme measures to keep fighting.

That’s the beginning. That’s the sane part. Then the screaming begins.

Oh, and Giuliani shows up. And it goes on for about 6 hours until midnight.

It was remarkable that the presidency had deteriorated to such an extent that this fight in the Oval Office between senior White House officials and radical conspiracists was even taking place.

Yeesh, and I still see fanatics defending the Trumpkins.

Dance while the world burns

There was a military coup in Myanmar — the generals didn’t much care for who the people elected with a democratic vote, so they just rolled in and changed the results, deposing Aung San Suu Kyi and installing Commander in Chief Min Aung Hlaing to run the state. I am relatively happy that the military has a good policy to stay out of politics and wasn’t involved in our recent insurrection.

We need something surreal now and then, though. Here’s a video of a woman in Myanmar doing her workout routine while the coup quietly unrolls behind her.

One never knows what wonders await in abandoned spaces

How about a happier story? About finding treasure?

A fellow in upstate NY bought an old building and was renovating it, when he discovered an attic that had been closed and sealed over with drywall for about a century. He peeled away the old drywall, climbed up, and found…

With his friend Ian Boni, owner of Twisted Rail Brewing Company who also owns property in Geneva, the men stacked several chairs upward. Standing atop the teetering tower with a flashlight in hand, Whitcomb spotted several dust-and-soot covered gold-framed photographs.

He turned to Boni and said, “I think we just found the Goonies treasure.”

The two men came across what appeared to be a storage site of a vintage photography studio. The vaulted attic was filled with vintage photographs, framed pictures and photography equipment and boxes of materials.

They had uncovered contents of a turn-of-the-century photography studio, complete with props, chairs and backdrops. Boni said he didn’t recognize suffragist Susan B. Anthony or any of the other people featured in the dozens of photos he helped remove from the attic.

It had been owned by James Ellery Hale, a photographer from the turn of the previous century who was well known for his photos of the suffragette movement, so there are all these dusty photos and photographic plates of Susan B. Anthony and Elizabeth Cady Stanton and other, not yet identified figures of the early movement. This is amazing.

I checked out my house’s attic (it was built in the 1940s), but I’m afraid all I found was mouse poop and fiberglass insulation, darn it. But we do have a lot of old buildings in Morris, and now I’m wondering what treasures we could find if we had access.

They’re full of spiders, I bet!

Facebook is irresponsible, Zuckerberg deserves to rot in hell

You know, I’m sitting here in a pandemic unvaccinated because the need exceeds the supply, and I’m willing to defer to the priorities of the society I live in and will wait until my opportunity rolls around. I am confident, because I know how vaccines and the immune system work, that vaccination is the solution that will end the restrictions on travel and personal interactions. I also know, because I’ve read the empirical studies, that masks are a good stopgap to slow the spread of the virus. I also know and trust the authorities, like Tara C. Smith and Anthony Fauci, who have made a career of studying infectious disease.

These are reasonable, informed attitudes to take toward our situation. I suspect that the majority of readers here share my ideas. These ideas are not up for debate; the question of whether the germ theory of disease was valid was resolved long ago, there’s confirmed scientific evidence behind them, and if you want to question them, you’d better be a verified expert who has gathered an immense amount of observation and experiment to back up your challenge.

And then there are the goddamned idiots who get everything they know from circle jerks on Facebook. They translated their ignorance into a mob action at Dodger Stadium, actively preventing other people from getting vaccinated.

My rage is boundless. It’s bad enough that these assholes want to run around spewing viruses on everyone, that they defy the need to take basic precautions to limit the spread, and that they are upset because those precautions interfere with the need to get their precious Fifi to the dog-groomers, but now they’re forcing everyone else to not take the best preventive action we can do? Don’t they realize that the only effective way to end the lockdown that has limited movement and social events, and to get rid of the masks that annoy them, is for a majority of the populace to get that quick little shot?

No, they don’t. Because they get all their information from their equally ignorant friends and family on Facebook.

The anti-vaccine protest that temporarily cut off access to a mass vaccination site at Dodger Stadium was organized on Facebook through a page that promotes debunked claims about the coronavirus pandemic, masks and immunization.

The Facebook page, “Shop Mask Free Los Angeles,” issued a call last week to gather Saturday at the baseball park. Health authorities have been administering shots to as many as 8,000 people a day at the site, one of the largest vaccination centers in the country. Such venues form a critical component of the effort to corral the pandemic, which has lashed Los Angeles County so brutally in recent weeks that oxygen for patients has been in short supply.

The online activity illustrates the extent to which Facebook remains a critical organizing tool of the anti-vaccine movement, despite the company’s repeated vows to curb coronavirus misinformation. It also shows how social networking services could foster more confrontational tactics by those committed to false ideas about the dangers of immunization as the mass vaccination effort ramps up.

Jesus, but I hate Facebook. I’m still on it myself, because it remains the one way I can maintain contact with far-flung friends and family, but let’s face reality: Facebook is a giant information-harvesting operation that sells all the information it gathers to other big corporations and political organizations. That it allows me to contact an aunt I haven’t seen in 20 years, or see pictures of my nieces and nephews new babies, isn’t their business model. They’re there to monitor my personal information to sell to the highest bidder. I’ve signed up for alternatives like MeWe or Mastodon (I did not sign up for Parler or Gab, for obvious reasons), but they don’t have the critical mass, and there’s no point unless all the others I want to follow sign up as well.

Facebook does not care about misinformation or privacy or propaganda. All of the assholes got their marching orders from a Facebook page that spread to other Facebook pages that have been continuously spreading lies throughout the pandemic.

The page itself has only about 3,000 followers, but the notice about what it termed a “PROTEST/MARCH” at the mass vaccination site was shared extensively in Facebook groups and on pages fixated on false ideas about masks, such as that they restrict breathing and that the Constitution forbids mandating their use. Names of the online forums include “Anti-Mask REVOLUTION!” and “Unmask California.”

The technology giant committed at the end of last year to enhancing its policies against coronavirus-related misinformation. That included a pledge to remove misinformation about the safety, efficacy, ingredients and side effects of coronavirus vaccines.

In a sign of gaps in the company’s enforcement, however, the “About” section of the anti-mask page promoting the Saturday protest included a link to a website devoted to the baseless “Plandemic” narrative accusing shadowy elites of enriching themselves by engineering the coronavirus and a vaccine for it.

Yeah, sure, Facebook is “committed” to ending the spread of misinformation, just like Twitter was so committed to ending political dishonesty that they waited until the last week of his presidency to cancel Trump’s account. There is no investment in truth and accuracy anywhere in the Facebook/Twitter/Instagram business model. They’re all about drawing in users by feeding them what they want, and if they want poison, so be it. Poison is profit for Facebook, so trusting them to do the right thing is folly.

If social media are things the public finds useful, then what needs to be done is to regulate the fuck out of Facebook, put in punishments with teeth in them for spreading misinformation, and make the company executives directly accountable for the harm they do.

Not that that will ever happen. We’re just going to wallow in the shit the goddamn idiots make.

The Christian Right poisons everything

I know Christopher Hitchens’ motto was that religion poisons everything, but maybe we should be smarter about parceling out the blame. Here’s a fascinating thread by Jane Carnall about the history of splitting out the “T” in “LGBT”. In Scotland, the alliance of lesbian, gay, bisexual, and transgender people was basically taken for granted; in the US, the hate campaign against gay marriage was stopped cold by a Supreme Court decision. The Religious Right needed a new way to spew venom over non-cis non-heterosexual people, and they consciously decided that one way way would be to splinter the alliance.

So in 2017, at the Values Voter Summit held by the FRC (Patriarchy Research Council), they said it explicitly.

As Right Wing Watch also mentioned in their coverage of the same panel, a trend emerged during the session, as various speakers wrapped their opposition to nondiscrimination measures in rhetoric passing as progressive: transgender rights were depicted as anti-feminist, hostile to minorities and even disrespectful to LGB individuals. This seems to be part of a larger strategy, meant to weaken transgender rights advocates by attempting to separate them from their allies, feminists and LGBT rights advocates.

In her presentation, Kilgannon [a conservative activist] mapped out three non-negotiables in the fight against the so-called gender identity agenda, a conspiracy theory touted by anti-LGBT groups that disavows sexual orientation and gender identity. The first is to “divide and conquer. For all its recent success, the LGBT alliance is actually fragile and the trans activists need the gay rights movement to help legitimize them.” In other words, separate trans activists from the gay rights movement, and their agenda becomes much easier to oppose. As Kilgannon explained, “Trans and gender identity are a tough sell, so focus on gender identity to divide and conquer.” For many, “gender identity on its own is just a bridge too far. If we separate the T from the alphabet soup we’ll have more success.”

I’m rather impressed at how readily the Religious Right adopted feminist rhetoric to use against the open, tolerant views of LGBT feminists. Strategically it’s brilliant, even if it is hypocritical and morally repugnant, since they hate LGBs as much as they do Ts. They are consciously allying with a group they plan to stab in the back, once LGBT unity is weakened.

Kilgannon identified a wide coalition of potential allies outside the Christian Right who could confront trans friendly measures. Here’s her advice on how to draw them in:

Explain that gender identity rights only come at the expense of others: women, sexual assault survivors, female athletes forced to compete against men and boys, ethnic minorities who culturally value modesty, economically challenged children who face many barriers to educational success and don’t need another level of chaos in their lives, children with anxiety disorders and the list goes on and on and on.

The list could almost read like a manifesto for intersectionality, if it weren’t for its exclusion of some key groups, most notably transgender people themselves.

For Kilgannon, an example of effective coalition building includes the Hands Across the Aisle Coalition (HATAC), a group that unites religious and non-religious women to oppose transgender rights.

Yeah, good work, secular Americans. You were duped.

Let’s not forget that the Religious Right had reciprocal assistance from TERFs.

In many ways, there are possible allies to this pivot toward anti-trans secular movements: trans-exclusionary radical feminists, dubbed TERFs by some activists, have made waves in recent years. Some TERFs have reclaimed the term and redubbed themselves PERFs, penis-exclusionary radical feminists. Their rationale is that people who are assigned male at birth can never experience the same conditions as women do, and still hold on to their male privilege. (The latter becomes harder to prove in the face of the discrimination experienced by trans and gender non-conforming people.) As reported by Political Research Associates, trans-exclusionary feminists “may actually be guilty of drafting [the Christian Right’s] talking points, adding fuel to the fire of this dangerous anti-trans frenzy.”

I feel clarity coming on, like a nice cool draft of water. The barbarians who want to destroy our civilization and remake it in the stifling raiment of theocracy hate me for my atheism and science, despite the fact that I’m conventionally cis and hetero. They hate my friends who might be gay, or trans, or anti-authoritarian, or black, or liberal Christians, or Muslim, or any other that doesn’t conform to their views, and they are having remarkable success at picking off one narrow demographic at a time and weakening the bonds of our unity. We should know better here in the US, where the Religious Right has used single-issue rhetoric like an icepick against the body politic, splintering us into deeply divided blocs that they can manipulate. They’ve been using abortion, for instance, as a tool to get people to vote against their own interests, and now they’re gearing up to use anti-trans ranting to break us up further.

Stand strong, everyone. Don’t let disunity allow the Robertsons and Falwells and Copelands and all the other parasites to win.

Home from Wisconsin

We were out playing in the snow with Iliana. I asked her if it was OK if we took some selfies.

“Yeth,” she said.

So we did.

On the way home, we passed a person who said, “Oh, what a cutie pie!”

I wasn’t sure which of us the person was talking about, so a little further on, I asked Iliana, “Are you really a cutie pie?”

“Yeth,” she said.