Finally! Someone I agree with on the Russian interference

I believe Russia did meddle in American politics, at least in the sense of assisting Republican propaganda. I could easily accept that their tinkering, and partisan influence from what should be non-partisan bureaucracies (like the FBI) shifted the vote margins by a percentage point or two. You can even argue with me by how much of a percentage and I’d just shrug and go along with it.

But what made an even bigger difference, what really made Trump possible, was an incompetent, smug, conservative Democratic party that bumbled the election at every point. It looks like Matt Taibbi shares my opinion.

Did the Russians do it? Very possibly, in which case it should be reported to the max. But the press right now is flying blind. Plowing ahead with credulous accounts is problematic because so many different feasible scenarios are in play.

On one end of the spectrum, America could have just been the victim of a virtual coup d’etat engineered by a combination of Donald Trump and Vladimir Putin, which would be among the most serious things to ever happen to our democracy.

But this could also just be a cynical ass-covering campaign, by a Democratic Party that has seemed keen to deflect attention from its own electoral failures.

The outgoing Democrats could just be using an over-interpreted intelligence “assessment” to delegitimize the incoming Trump administration and force Trump into an embarrassing political situation: Does he ease up on Russia and look like a patsy, or escalate even further with a nuclear-armed power?

Emphasis is mine. All the news about Russian interference is just playing to the media and giving the DNC an excuse, all while distracting the party from actually confronting their deep internal problems and doing something about it.

Because, I fear, they don’t want to do anything about it.

FishFace

fishface

That’s no insult, it’s a zebrafish craniofacial development website. It’s cool that it’s managed by my graduate advisor, Chuck Kimmel, but it’s also full of images of zebrafish skulls (fish skulls in general are amazingly beautiful, with all kinds of delicate detail). I’m pining for a confocal microscope of my very own now.

It’s also a subset of FaceBase, an even grander collection of data on craniofacial development in those lesser creatures, humans and mice. If you’re interested in the formation of the head and neck — and you should be, those are complex hotspots for all kinds of developmental disorders — check it out.

I don’t wanna make book recommendations

It’s that time of year when I think everyone got Amazon gift cards and then they go asking me to make book recommendations. It’s hard. Writing a science book is even harder. And there are a lot of bad science books out there.

One problem is that everyone wants the shortcut: there’s a hot new science topic, lots of people are curious about it, they want to know more, the publishers see an opportunity, so they commission a flashy pop sci book that will sate that curiosity. And it’s garbage, because it’s written by people who don’t know the basics, or because it’s written for people who want to hear that the answer is magic. Case in point: there are no good popular books about epigenetics right now, as far as I can see. If it’s got “epigenome” in the title, just scratch it right off your list. This may change, I hope it will change, but it’s an example of a topic where the situation is rather dire. That’s unfortunate, because it’s an important topic.

At the other extreme, there are the textbooks. There is a reason that textbooks exist, and it isn’t just the venality of publishers and the conservative nature of professors: they are dense repositories of basic knowledge. My genetics class uses Klug’s Concepts of Genetics, it’s not light reading, and to get the most out of it you should actually sit down and do the problems at the end of each chapter. Does that sound like fun? How does the $196 price tag sound to you?

There is a sweet spot in popular science writing where the author manages to simultaneously explain the basics and get them right, while also getting the big picture explained in an interesting way. Carl Zimmer consistently hits that target, Sean B. Carroll is good, Adam Rutherford’s Creation does a fine job of covering biotech and the origin of life, Nick Lane is always amazing. The microbiome was one of those buzzwords that spawned a lot of crap books, like the word “epigenetics” now, but Ed Yong rose above the dross and came out with a good general science book on the subject.

But it’s still really difficult to address requests for recommendations. Usually it’s because someone wants an answer that they can digest in a couple of days of light reading, and often, that can’t be done.

The correct answer is that what you need to do is register at the University of Minnesota and sign up for my classes. I’ll whip you into shape in 15 weeks of harsh discipline.

It’s the same old racist genetics

Another domain the alt-right neo-Nazis want to claim for their own is genetics. Sarah Zang has a very good overview of how the deplorables are eyeballing modern genetics and genomics, and mangling it to support their racist theories, titled Will the Alt-Right Peddle a New Kind of Racist Genetics? My only objection would be that this isn’t a new kind of racist genetics at all — it’s the same old garbage, in which they misinterpret results to support their preconceptions. The interesting thing, though, is that geneticists are gearing up to fight back.

Jedidiah Carlson was googling a genetics research paper when he stumbled upon the white nationalist forum Stormfront. Carlson is a graduate student at the University of Michigan, and he is—to be clear—absolutely not a white nationalist. But one link led to another and he ended up reading page after page of Stormfront discussions on the reliability of 23andMe ancestry results and whether Neanderthal interbreeding is the reason for the genetic superiority of whites. Obsession with racial purity is easily channeled, apparently, into an obsession with genetics.

Stormfront has been around since the ’90s, which means it’s been around for the entirety of the genomic revolution. The major milestones in human genetics—sequencing of the first human genome, genetic confirmation that humans came out of Africa, the first mail-in DNA ancestry tests—they’re all there, refracted through the lens of white nationalism. Sure, the commentators sometimes disagreed with scientific findings or mischaracterized them, but they could also be serious about understanding genetics. “The threads would turn into an informal tutoring session and journal club,” observes Carlson. “Some of the posters have a really profound understanding of everyday concepts in population genetics.”

Carlson has been arguing with the bozos on Twitter, and I’ve been occasionally bouncing off them here and there — the “human biodiversity” gang, their intentionally neutral term for pseudo-scientific racism, kinda despises me. Even before I read this article, though, I was working up some new material for the genetics course I’ll be teaching in January specifically to address some of these problems at a fairly basic level.

One concern I’ve had for a while now is that often in undergraduate genetics we’re teaching a kind of simplified Mendelism as a starting point, and in the lab we do crosses that have been time-tested for clarity and consistency. Students start out with this kind of crude beanbag genetics in their heads, which actually is a good beginning point to get the concepts across, but then when we get into real genetics, that is considerably messier and more difficult, they may flounder. At least, that’s been my experience; but we also see it in the general public where they got a bit of Mendelian pea-crossing in high school, and then they hear something about epigenetics and just go off the rails.

This year I think my first class will involve throwing examples at them of unexpected genetics, stuff that doesn’t fit their high-school version, and start ’em out by preparing them to not trust simplistic interpretations, and to realize that Mendel’s results were a starting point for a model. It’ll also help to let them know that they don’t know everything right from the first day.

But then we’ll go right back to Mendel, and work our way up from that foundation to the hard, fun, bewildering stuff. And maybe I should try to include at least a little section on the genetics of race near the end. The garbage that Stormfront is peddling has been around for a long time, and maybe we need to start addressing it at the undergrad level now…and yes, at the high school level. I’ll have to leave that to the high school science teachers out there reading this.

“Spokane, Washington’s Most Single Man”

One man’s quest: to have sex with teenagers. His tools: misconceptions about biology, access to a meme-maker, and boundless self-pity. Ladies, meet Lucas Werner…and run away.

He’s an atheist in Washington state, going by the name “OlympiaAtheist” on facebook. I wish he wouldn’t. Atheists have enough reputation problems as it is.

His obsession — it really is an obsession, it’s basically all he writes about — is that he’s 37 years old, he wants a girlfriend who is less than half his age, and that he thinks he is biologically entitled to have sex with younger women. His strategy is to create terrible, terrible meme images and post them on the web, which I’m sure is going to draw in the high school girls like bees to honey. Here’s one example. There are many more.

pedomeme6

You should have sex with him, because he has lower telomerase levels than younger men, and therefore he’s not going to give you cancer. And you’re a bigot and a hypocrite if you don’t take him up on his kind offer. Here’s a photo of a bridge.

[Read more…]

A day of mourning

I take it all back. 2016 sucks.

You know how when someone you love is in pain, and there’s not one damn thing you can do about it? It’s also personal and private, so I’m not going to discuss it, but at least I can show you how I feel.

We’ll all get better. But everything is going to be a bit raw for a while.

The celebrity death toll is a matter of perception

abevigoda

We hear a lot about how awful the year 2016 has been…but have the obituaries actually been that frequent? Greg Laden compares the number of celebrity deaths this year vs. other years, and the answer is no. Which is actually what I expected — there is no causal mechanism and no selective agent making a particular year more lethal than other years.

deadcelebsaccordingtotvguide

Now if we’d had a global war, a civil war, a plague, and a collapse of society (wait until 2017 for those!), then we’d have a reason to expect a surfeit of deaths. I wonder how Syrian celebrities are faring this year?

Otherwise, though, I think this was a self-fulfilling prophecy. All it takes is the death of a few celebrities, a little nudge of superstition, like the rule of threes, and soon enough people are doing all the work for you, gleaning every mention of a death and throwing them into the tidy category of “2016!”, and that reinforces the story. You can’t remember every celebrity who died, but you can remember “a lot of celebrities died in 2016”, and that becomes the memorable link.

Alternatively, all the people who sold their soul for fame and fortune are being recalled this year because the stony-faced guardian of the portal to Hollywood Hell, Abe Vigoda, died in January 2016, unleashing a swarm of vengeful demons.

Now be honest: Who remembered that Vigoda died early this year? How many of you are now adding his name to the tally of 2016 deaths, reaffirming the myth?