Here’s a clever (I think) observation in the efforts to eradicate malaria: the mosquitos that transmit malaria are also infected with the disease-causing parasite, so maybe if we cure malaria in mosquitos, it will end one intermediate step in the transmission chain. It sounds like a crazy idea, but recent experiments suggest that it might just work. It’s got the advantage of allowing the use of transgenic techniques on the mosquito population, where you don’t have to worry about patient’s rights or whether a few of your experimental subjects will die during the procedure, and you can just let the untreated population wither away and die, and no one can complain. There are a few other ethical concerns, however.