1. chigau () says

    So. You are doing this from the airport?
    That picture looks just like my high school principal.

  2. DLC says

    The good thing about having a shell is, you have your own house which you can take with you wherever you go.

  3. nemo the derv says

    He looks comfy. Someone needs to put a “sold” sign in front of that shell because I think he just bought it.

  4. Freerefill says

    Makes me wonder if this is going to be a new evolutionary path for them. Just like birds build nests, are these cephalopods going to instinctively seek out shells or bottles to hide in/under, and carry them around wherever they go? That would be SO cool.

  5. QwertySapiens says

    So I wanted to see if anyone can tell me how big a deal this is:
    It’s a paper published recently by a lab at MIT which says that they’ve created a chimeric protein that interferes with any cell with viral dsRNA in it by initiating a apoptogenic cascade. This has been proven true over 15 different viruses from different families. Is this possibly as important as, say, penicillin?

  6. Fukuda says

    Qwerty, I remain a bit skeptic about that approach.

    Mostly because we already have equivalent proteins inside our cells. The RIG helicase protein family does exactly that, it detects double stranded RNA and activates among other things an apoptotic cascade.

    Most viruses are able to circumvent the mechanism (obviously, we wouldn’t have infections if not) even though they usually do it blocking a step between the helicase and the apoptotic effectors.

    The novel thing is that they pasted the dsRNA recognition domian of a RIG protein to an apoptotic effector activating domain (Apaf1 or FADD). That’s neat as it solves any problem caused by a blockade of the signaling pathway, but most viruses are able to block the apoptotic effectors themselves (caspases).

    Viruses acquired an entire arsenal of anti-apoptotic proteins through evolution.. And they certainly will continue acquiring them if we apply enough selective pressure on them…

    Not saying that it’s not a great approach, just that we shouldn’t get our hopes way too high.

  7. Audley Z. Darkheart OM, purveyor of candy and lies says


    He is ready for the weekend! Where’s his beer?

  8. QwertySapiens says

    Thanks! Sometimes it becomes difficult to filter the “OMGBESTNEWCUREFOREVERYTHINGEVAR” from the reality, and on those occasions I’m glad I have the Pharyngula community to turn to :).

  9. Audley Z. Darkheart OM, purveyor of candy and lies says

    QwertySapiens, if you have another question like that, you can bring it up on the Endless Thread– nothing is off topic there.

    The latest one can be found here: Episode CCXLII: Yikes!


  10. Celeste says

    I know it’s just the angle of the picture, but it looks like someone crossed a warthog with an octopus.

  11. 'smee says

    Gel? WTF is Gel?

    That should read Glen (my humblest, most abject, and heartfelt apology shall wend your way, once I find a heart)

  12. mouthyb, powered by spite since 1977 says

    I was not aware how stinking cute those critters could be until reading pharyngula.

  13. says

    If I recall correctly, these octopodes in the coconut shells are found near the Philippines in places where the sea floor is barren and there is little shelter from predators. The shells are vital protection and the octopodes carry them around rather than leaving them for another to find. At the sight of a large fish, they retreat into the shell and flip it over to make a hut.

    The same area has the mimic octopus, which can look and move like more than a dozen other animals including a flounder and a venomous sea snake, and a blobby thing that I think is meant to convey stonefish (which has poisonous spines).

  14. TJ says

    So, what’s the deal here. Are we supposed to go to Pharyngula on this site or the other.