Comments

  1. Sili, The Unknown Virgin says

    Well, durrrr. Lenski wouldn’t give him the samples, would he now.

  2. SteveM says

    50,00 generations and have any of them evolved into strawberries? No? Evolution FAIL!

  3. Porco Dio says

    yeah right…

    so if humans have evolved from bacteria why are there still bacteria?

  4. Steve LaBonne says

    The truly beautiful experiments are disarmingly simple in concept yet are able to probe deep into the heart of nature. Lenski’s long term E.coli project is one of the most beautiful experiments in biology in my lifetime.

  5. Brownian, OM says

    .Their project in bacterial evolution in the lab has reached the milestone of 50,000 generations.

    .

    Probably should have stopped at two. By the time they got to Bacteria: Enterprise they had nowhere to go and had to reboot the series.

  6. Greg Laden says

    But I understand that they don’t allow peanut butter in that lab, so who’s to say, really?

  7. IslandBrewer says

    Obviously, Lenski is lying, because all scientists lie. Lenski has also failed to send the bacterial samples that explain motherfucking magnets.

  8. rrpostal says

    There are times in between the pillaging and football rapists in the news that actually make me proud of my alma mater.

  9. Glen Davidson says

    Has the bacterial flagellum re-evolved?

    If not, then Behe’s right, because, uh, he ignored all of the evidence of evolution and demanded something that he knew couldn’t be realistically reproduced.

    So he wins — the title of Anti-scientist.

    Glen D
    http://tinyurl.com/mxaa3p

  10. sacredchao2305 says

    So, my wife’s a biology phd student, and I’m just a lowly film grad trying to get into a fiction MFA program. When I read The Greatest Show on Earth, I got really excited when reading about this experiment, so I started ranting about how awesome it was and all that. She just kind of said, “yeah, I know about it already.”

    Grrr. Damn scientists. Always lying knowing stuff before I do and getting me pissed.

  11. Brownian, OM says

    I can not wait to taste braised Crocoduck.

    I wonder if it’ll taste like chicken, or just blasphemy.

  12. Rev. BigDumbChimp says

    I wonder if it’ll taste like chicken, or just blasphemy.

    I hope both

    mmmmmmm sacrilicious.

  13. 'Tis Himself, OM says

    But does it explain DWARFS + PYGMIES!!?!?

    It doesn’t even explain DWARF + PYGMY E coli.

  14. Nebula99 says

    They’re still going? That is one long-term experiment! I wonder how much they’ve changed in 50k generations. I know some became able to digest a new substance (citrate IIRC); does anyone know any other cool things they’ve done?

    mmmmmmm sacrilicious.

    But is it better than roasted baby with a side of watermatoes?

  15. blf says

    50,000 Andy Schlafly’s? Eeeooowwwww…

    (I now needs to go wash my traumatised brain with cilantrosoap.)

  16. Benjamin Geiger says

    A serious question:

    How does one count the number of generations of bacteria, especially to that level of precision? Is it possible that they’re actually around 48,520, or maybe 53,211?

    Or do they mean 50,000 iterations?

  17. Brownian, OM says

    I know some became able to digest a new substance (citrate IIRC); does anyone know any other cool things they’ve done?

    Shhh! I don’t want my mother to hear.

    “Hmph. So these bacteria evolved the ability to digest citrate and you can’t even find yourself a nice girl to settle down with. And when are you going to get yourself a better job? Would it kill you to shave that scruff? Everyone’s going to think I didn’t teach you proper hygiene.”

  18. James F says

    But they’re all still the same bacterial “kind,” right? Which baramin is E. coli, again? Must email Richard von Sternberg….

  19. Die Anyway says

    >Congratulations to Richard Lenski and his lab

    Hmmmpphh, I thought this was going to be a nice “man and his dog” story.

    Anyway, I do remember reading the Lenski/Schlafly story before but it was great fun reading it again. Lenski writes almost as well as PZ.

  20. Ewan R says

    They’re still going? That is one long-term experiment! I wonder how much they’ve changed in 50k generations. I know some became able to digest a new substance (citrate IIRC); does anyone know any other cool things they’ve done?

    Inverted about 1/4 of their genome (2009 nature paper has complete genome sequencing data of a line at 2,5,10,15 and 20k generations showing the appearance of an abundance of conserved mutations – not sure the inversion is particularly meaningful in terms of adaptation, but it is rather nice to see such a dramatic genome alteration occuring), and altered their DNA topology so as to replicate better/faster (amongst other stuff)

  21. Sili, The Unknown Virgin says

    Wow, that’s a lot of missing transitional forms!

    Only 49.999. Still plenty more consistent than the Bible.

    Shhh! I don’t want my mother to hear.

    Who cares what she thinks? Go blow some more boys under the bleachers.

  22. PeteGrimes says

    Wow – I can’t believe I didn’t hear about this back in ’08!?!?

    I had a terrific time reading through the entry on rationalwiki.

    Behold! The Power of Science!

  23. mikerattlesnake says

    @23

    Tell her your Great (x 49,997) grandkids will have it figured out.

  24. Brownian, OM says

    Who cares what she thinks? Go blow some more boys under the bleachers.

    Sili, what happens in the Endless Thread…

  25. tsg says

    Sili, what happens in the Endless Thread…

    can and will be held against you….

  26. Steve LaBonne says

    Also cool: the 12 separate lines achieved similar (but not identical)increases in growth rate and cell size via substantially different genetic pathways, a striking demonstration of convergent evolution in molecular detail.

  27. Sili, The Unknown Virgin says

    can and will be held against you….

    Ooo-ah. Don’t mind if I do, matron.

  28. chaseacross says

    Wow, in addition to being a brilliant biologist, Zachary Blount also has some pretty fine calligraphy skills.

    I wonder how many generations it takes for creationism to get weeded out…

  29. Kel, OM says

    Their project in bacterial evolution in the lab has reached the milestone of 50,000 generations.

    Yet the bacteria is still just a bacteria. *sigh* When will evolutionists learn that you just can’t get from bacteria to bipedal ape human? In 50,000 generations there’s no even a leg or even half a leg (which by the way is absurd *chortle*).

  30. Alex the Wonderchemist says

    I can never get to the end of the Lenski Dialogue, I’m always laughing too hard at how severe a beat-down Schlafly got.

    In the over-used terminology of the internet generation: Epic pwnage

  31. amphiox says

    Damn scientists. Always knowing stuff before I do

    Happens to scientists themselves all the time, too. Which is why they get so excited when they’re the very first to discover something. (Only for it to be discovered five years later that some schmo had basically the same idea 10, 20, 50 or even 200 years ago, but never published….)

    I wonder how many generations it takes for creationism to get weeded out…

    New mutant versions keep popping up due to memetic drift every 10 years or so. Hmm, if we could calibrate this with the creationist fossil record (“cdesign proponentsists” dates to circa 1989? Or was it 1993?), we could develop a memetic clock for data idiocy.

  32. amphiox says

    Oops. That’s “dating idiocy”.

    On second thought, “data idiocy” is a perfect descriptor of Dembski.

  33. BlueMonday says

    @sacredchao2305
    I just finished writing a play that includes a scene in which a man regales his date with the finer points of the Lenski experiment. It’s implied that she pretends that she hadn’t heard of it in order to let him tell her something sciency for once (instead of the other way around).

    It’s both fun AND educational! It may even get produced someday. Perhaps a film version? *wink wink nudge nudge*

  34. KillJoy says

    I’m focusing on ‘blowing boys under the bleachers’.
    Apparently I should read the endless thread more often. :P

    KJ

  35. Ichthyic says

    I’m focusing on ‘blowing boys under the bleachers’.

    good luck with that.

    O.o

  36. KillJoy says

    Boy that came out wrong.
    I’m going to go over here and be embarassed now. :P

    KJ

  37. TheNP says

    rrpostal… It’s always a good day to be a Spartan. Mainly because of this sort of research and Izzo.

  38. Brownian, OM says

    Apparently I should read the endless thread more often. :P

    Maybe one day I’ll explain how I briefly earned the moniker of “Mr. Hoover.”

    [/intentionally vague and misleading partial details]

  39. cuco3 says

    This is just such a beautiful, beautiful experiment. Such fascinating results, and the discipline and determination to stick with it all this time.

  40. ambulocetacean says

    A brilliant experiment, and no doubt incredibly fiddly. I’m sure I would have accidentally spilled my coffee all over it before it got to 10 generations. I can’t wait to see what happens at 100k. With or without coffee.

    Schlafly is an idiot. And a world-class ignoramus. He says since he’s never heard of University College, London, it must be a crap school. Oh, and he says that nobody has ever seen a black hole, so scientists just invented them to stop people reading the bible.

  41. Mak says

    The sarcasm in this thread is so thick it has gained physical form and is suffocating me. *gack*

  42. Zeno says

    Soon Lenski will be able to announce that his E coli have evolved to a level of intelligence equal to Andy Schlafly’s.

    (Actually, it was a act of kindness that Lenski did not make the announcement after generation 1.)

  43. Aegis Linnear says

    I love that the Lenski affair link PZ posted contains the phrase ‘response to creationism’ which has an integrated link to the wiki for the word ‘Pwned’. Sums it up perfectly.
    Congratulations, Professor Lenski! Next step’s to let it evolve until it feeds off very very old paper and loose it in the Vatican…or it would be, in an ideal world. XD

  44. God says

    Both Lenski and Schlafly are fools. I designed a new citrate-using bacterium and created a prototype in Lenski’s laboratory, for reasons that only I can understand in My infinite wisdom. Even Behe hasn’t seen the light yet.

    Speaking of dating idiocy, it angers me to no end. Why can’t people simply buy their brides according to My principles?

  45. monado says

    Maybe they should start feeding their microbes oil. Actually, I think there are oil-eating bacteria, and we really don’t want them to mutate to the point where they are munching oil reserves, gas, kerosene, and plastic.

  46. blf says

    Maybe they should start feeding their microbes oil.

    Eating BP executives might be better.

  47. David Marjanović says

    How does one count the number of generations of bacteria, especially to that level of precision? Is it possible that they’re actually around 48,520, or maybe 53,211?

    Each generation you have twice as many bacteria as before. Just measure how many spill out of the experiment every day.

    The sarcasm in this thread is so thick it has gained physical form and is suffocating me. *gack*

    Alternatively, someone is finding your lack of faith… disturbing.

  48. danielm says

    ahha! it’s so obviously fake, because now there are 49,999 missing transitional forms!

    with that many missing pieces, it can’t possibly be reliable!!!!1111oneoneoneone

  49. Janey Mack says

    @ Brownian, OM (#45)

    Once upon a time, a feast in Cavalier style was held. At the conclusion of said feast, the clean-up crew discovered that the vacuum cleaner on the premises (I believe it was a church) was out of order. Upon hearing this information, the young lady hostess of the event turned to the various members who were lingering in convivial gossip, as people do at such things, and announced,”The vacuum cleaner isn’t working so we’re going to need your help. Everybody down on your knees and suck!”

    I didn’t know people could turn that shade of scarlet! (No, it wasn’t me. But I understand how these things can happen…)

  50. Sven DiMilo says

    Each generation you have twice as many bacteria as before. Just measure how many spill out of the experiment every day.

    Actually they control the nutrient supply to get 7 doublings per 24-h period, if I remember correctly.

  51. Bruce Godfrey says

    I think there should be a song written of the “begats” along the lines of “Dem Dry Bones.”

  52. Sili, The Unknown Virgin says

    Maybe they should start feeding their microbes oil. Actually, I think there are oil-eating bacteria, and we really don’t want them to mutate to the point where they are munching oil reserves, gas, kerosene, and plastic.

    I read about a high school science project where the kid had collected earth samples from whatchmacallems garbage heaps and then grew the bacteria in them on slurries of ground-up plastic. Turned out some of them lived nicely off the synthetics. I certainly hope more’ll be made of such discoveries.

  53. amphiox says

    Eating BP executives might be better.

    What have you got against those poor innocent microbes?

    Nothing deserves the torture of being force fed that kind of poison.

  54. bhoytony says

    If you want to hear an awesome rendition of the “begats” then look no further than this:

    http://www.chriscoltrane.com/lee_and_herring/downloads/Richard%20Herring%20-%20Christ%20On%20A%20Bike%20-%20Pleasance,%20Edinburgh%20-%202001.mp3

    Richard Herring’s comedy monologue “Christ On A Bike” from the 2000 Edinburgh Festival.
    Realising he was 33, the same age as Jesus when he died Herring compares himself to Christ, “I’m not claiming to be the Messiah, that’s for others to decide.”
    In order to sort it all out he challenges Jesus to a bicycle race.
    It’s the full show so it’s quite long, but I think it’s hilarious. Well worth downloading.
    Herring’s old partner Stewart Lee and his show, “Jerry Springer, The Opera” was the driving force behind the changing of the UK’s blasphemy law.