Can aging be stopped?

The dream of some people has been that we can slow down, stop, or even reverse the aging process. Amelia Hill writes about recent research that argues that the aging process is unstoppable.

Backed by governments, business, academics and investors in an industry worth $110bn (£82.5bn) – and estimated to be worth $610bn by 2025 – scientists have spent decades attempting to harness the power of genomics and artificial intelligence to find a way to prevent or even reverse ageing.

But an unprecedented study has now confirmed that we probably cannot slow the rate at which we get older because of biological constraints.

The study, by an international collaboration of scientists from 14 countries and including experts from the University of Oxford, set out to test the “invariant rate of ageing” hypothesis, which says that a species has a relatively fixed rate of ageing from adulthood.
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Recall madness

The state of Missouri is known as the ‘Show-Me state’ but perhaps it should be renamed as the ‘Don’t bother to show me, my mind is already made up’ state. It has one of the lowest rates of vaccination in the country and some of the counties have extremely low rates. Naturally covid-19 cases are surging there. But the good citizens of the small town of Nixa have more important concerns.

Nixa, which has about 21,000 residents, is located about 10 miles (16.09 kilometers) south of Springfield, where hospitals are overflowing with COVID-19 patients.

Health officials are blaming low vaccination rates and the delta variant, first identified in India, for the surge. Just 44.8% of the state’s residents have received at least the first dose of the vaccine, compared to 54.9% nationally.

And the rate is even lower in southwest Missouri. Christian County, where Nixa is located, has a vaccine rate of 35.2%. Some nearby counties have rates in the teens.

The mayor of Nixa instituted a face mask requirement in October of last year, under a mandate authorizing him to do so issued by the city council. The mandate was lifted in April. Now he is facing a recall because of his action. The recall will cost the small town between $10,000 and $15,000. But it appears that for the good people of Nixa, no price is too high to pay for having the freedom to act stupidly contrary to the evidence.

Oc course, the people of the state of California have no reason to feel that smug. They have been able to get enough signatures for a recall election of the governor because of his actions to curb the pandemic.

A surprisingly early California recall election has Gov. Gavin Newsom looking to capitalize on his momentum and Republicans trying to catch up.

State officials have called the election for Sept. 14, and ballots will hit mailboxes weeks before then. The short timeline, enabled by Democratic allies of the governor, buoys Newsom’s prospects as he looks to convert a rebounding economy and stabilizing poll numbers into a vindicating victory. His conservative foes, on the other hand, have just two weeks to declare their candidacies and a tight window to cut into Newsom’s overwhelming fundraising advantage.
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It has been clear for months that voters would decide Newsom’s fate in 2021 after anger over his Covid-19 restrictions led two million Californians to sign recall petitions.

What a waste of time and money.

Caffeine addiction

My daily caffeine intake consists of one regular-sized cup of instant coffee (with milk and sugar) in the morning and one regular-sized cup of black tea (with milk and sugar) in the late afternoon. This would not normally be seen as a sign of caffeine addiction except that on the days that, for whatever reason, I cannot get my morning cup of coffee (in the case that I have spent the night at some place where I cannot get one first thing), I feel a little unsettled and will often go to some lengths to find a coffee shop where I can get a cup.

Food writer Michael Pollan says that that feeling first thing in the morning is indeed a sign of caffeine addiction, that my vague need to drink a cup of coffee is because the caffeine withdrawal symptoms are kicking in and I need to suppress them.
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Hilbert’s Hotel shows why some infinities are bigger than others

Here is an entertaining video that has a nice explanation of a seeming paradox about infinities.

In 1924, the German mathematician David Hilbert raised a peculiar and seemingly paradoxical question: are some infinities bigger than others? The answer he arrived at – yes, actually – might have been impenetrable to non-mathematicians if not for the thought experiment he devised involving a hotel with an infinite number rooms. This video from the Australian filmmaker and educator Derek Muller builds Hilbert’s ‘infinite hotel’ and populates it with some strange, fuzzy creatures to demonstrate how the mathematician arrived at his groundbreaking conclusion, and touches on the real-world implications of his discovery.

Would I stay or would I go?

The horrific collapse of a 12-story beachfront condominium building in Florida consisting of 136 units has resulted in 16 people being killed and another 149 still missing. While it will take some time to determine the cause of the collapse, suspicions are focused on problems with the foundations or that the salty air caused the steel used in the framework to corrode. A letter written by the president of the condominium association three months before the collapse said that the building needed $15 million in major maintenance and repairs.

There is another identical building just one block away that was built by the same company at the same time forty years ago and now those residents have to make the decision as to whether to stay or leave. This is not an easy decision and would depend on many factors. These units are expensive but their value would have dropped now and some people may not be able to sell and find another place. It would also depend on whether they lived alone (in which case they would only be risking their own demise) or whether they lived with loved ones which might tilt the decision towards moving. It would also depend upon age. Older people find it harder to move and may also feel that they have less to lose by staying.
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The Covid Delta variant is hitting the unvaccinated

The Delta variant of the SARS-CoV-2 virus is now rapidly becoming the dominant strain. This variant is more easily transmissible and more dangerous, and Dhruv Kullar warns that from the evidence gained so far from the UK, it poses a greater risk to the unvaccinated.

Earlier this year, scientists estimated that lineage B.1.1.7-the Alpha variant, first isolated in England-could be some sixty per cent more transmissible than the original version of sars-CoV-2. Now experts believe that the Delta variant is sixty per cent more transmissible than Alpha-making it far more contagious than the virus that tore through the world in 2020. It hasn’t yet been conclusively shown that Delta is more lethal, but early evidence from the U.K. suggests that, compared to Alpha, it doubles the risk of a person’s being hospitalized. Even if the variant turns out to be no deadlier within any one person, its greater transmissibility means that it can inflict far more damage across a population, depending on how many people remain unvaccinated when it strikes.

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The UFO/UAP story will never die

The US government has released its much awaited (by UFO enthusiasts at least) report on what it calls Unidentified Aerial Phenomena and it is just what you might expect.

The mystery of UFOs seen in American skies is likely to continue following the release of the US government’s highly anticipated UFO report.

The report released on Friday afternoon made clear that while American intelligence officials do not believe aliens are behind the UFOs – or what scientists prefer to call unidentified aerial phenomena (UAP) – that were observed by navy pilots, they cannot explain what the flying objects are.

The report confirms that the observed phenomena are not part of any US military operations.

The Pentagon studied over 140 incidents reported by navy pilots of UAP seen over the last two decades for the report. Many were seen from the summer of 2014 into the spring of 2015.

While the report said that some incidents could be the result of technological errors in sensors or observers, it noted that most of the UAP reported “probably do represent physical objects” since they were registered across multiple sensors.

The only UAP intelligence officials were able to identify “with high confidence” turned out to be “a large, deflating balloon”.

“The others remain unexplained,” the report reads.

There are two things to keep in mind. (1) There are always unexplained phenomena. (2) One can never rule out a favored hypothesis for any unexplained phenomena. Those two will ensure that people who believe that extraterrestrials are, for some reason, choosing to buzz around us without making contact will never run out of reasons to believe.

I for one am going to wait until one of them unambiguously contacts us before getting all excited.

Ohio anti-vaxxers want the freedom that vaccination brings

Now that the numbers of people who have been vaccinated has reached more than half the US population, there are places that require proof of vaccination before you can enter. Where I live in Monterey, CA, the local bridge club opened for face-to-face play on Tuesday but you have to show proof of vaccination before you are allowed to do so. The first time you go, you show the proof and your name is entered in a register and that eliminates the need to show proof each time. Masks are not required but you can choose to wear one if you like. There are bottles of hand sanitizer at each table and players are encouraged to use it frequently, especially since they are exchanging cards. I went on Tuesday and there were about a dozen people, about half of them being those who had been starved of bridge because they either were not comfortable enough with technology to play online or they had eye issues that prevented them from looking at a screen for any length of time. It was nice to meet them again.
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The origins of the SARS-CoV-2 virus

Recently there has been an upsurge of interest into the origins of the SARS-CoV-2 virus, the one that causes covid-19, with speculation that it may not have originated by mutating spontaneously into a form that could transfer from animals to humans but that it may have been leaked from a research laboratory that does work on such viruses. Most proponents of the lab leak theory have suggested that the leak was accidental but a few have suggested a darker possibility of deliberate release.

I have been trying to make sense of the debate and found this article by Mara Hvistendahl to be helpful in sorting through the various claims. Hvistendahl had been in China when the avian flu virus broke out in 2013 and she had visited the lab of a prominent researcher and avian flu expert Chen Hualan who had been doing the so-called ‘gain of function’ research that is seen by some as an indicator that the covid-19 virus did not come about by accident.
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E-scooters

These electrified versions of a child’s toy are becoming a popular form of adult transportation, able to travel at speeds up to 30mph (50km/h) and even carry two people. One can see their appeal, especially in urban areas, since they reduce traffic congestion, are maneuverable, easy to learn, and do not take up much space. But because of the reckless riding of some people, they are posing a risk to pedestrians.

French police are searching for two women after the death of a pedestrian who was hit by an electric scooter in Paris, officials say.

The 31-year-old victim, an Italian citizen named only as Miriam, was walking along the Seine early on Monday when she was hit by the e-scooter.

The pair were reportedly travelling at high speed, and did not stop.
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The case has renewed the debate over e-scooters in Paris, where there have been concerns for the safety of pedestrians.
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In 2019, the French government introduced rules after hundreds of incidents, including several deaths. Riders are required to be at least 12 and cannot ride their scooter on the pavement.

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