Pharyngula
Evolution, development, and random biological ejaculations from a godless liberal
This short film is intended to “raise awareness of the growing disappearance of honey bees”, a worthy goal, but all I could think while watching it is “ROBOT BEES ARE AWESOME!” I doubt that is the response they want.
Besides, we’re nowhere near making tiny robots as elegant as real bees.
GREENPEACE – NEW BEES from Polynoid on Vimeo.
Perhaps you are a sociopath with no social skills whatsoever, but you have decided that you love some other person, and unfortunately, that other person is marrying someone else. They must be mistaken, you think. They’ve made this big public commitment to a different person than you, but you just know that you are the love of their life. What to do? WikiHow provides a detailed, step-by-step procedure on how to stop a wedding, including everything from the prenuptial approach, in which you have a calm and collected
talk with the bride and groom, to the optimal place to sit for maximum effectiveness when you raise your hand and say I OBJECT
during the ceremony.
And then you get to Enjoy life with your stolen bride or groom.
Eww.
The only sensible part of the advice is in Step 7 of Before the wedding,
where it says Recognize a lost cause when you see one.
Yeah, I generally think the time to recognize that is when the other person announces that they’re getting married.
Further creepiness: if you are spurned in your efforts, wait until after the honeymoon and send an email or text asking to meet up.
No, please don’t.
There are about 16 steps in this list. I’m imagining some hopeless person printing out the whole thing and checking items off one by one as they plan to disrupt someone else’s life.
(Unless you’re clinically depressed, in which case being told to cheer up will not help at all, and even videos of hamsters eating tiny burritos won’t be enough.)
All that naked Greek statuary, with all their naughty bits hanging out…someone had to document ancient Greek testicles, and that person was Ingrid Berthon Moine.
Hey! Hey you! My eyes are way up here! I’ll have you know I’m much more than just a pretty ball sack…although the boys are spectacular, if I do say so myself.
When we bought our house, it came with a disconnected, nonfunctional hot tub. It’s still here, sitting unused in our back yard, because having a mere Ph.D. in biology means that I don’t know how to fix it, and also, I don’t get paid enough to afford to have it fixed by a competent hot tub expert. And thus am I made to realize that I am a failure. I shouldn’t have wasted effort on that lowly science degree; instead, I should have learned how to install hot tubs.
Because hot tub experts are wizards, masters of all knowledge and the mysteries of space and time.
I have been reading the works of James Arjuna, International Spa Design Engineer, who is a real scientist. He said so.
I am a real scientist for over 47 years. I make my living producing functional equipment that always works as designed because I don’t use any pseudo science. I hate pseudo science religious crap in academia.
He says so frequently.
Please check out my science blog. It is based on over 47 years of using the scientific method to solve problems and to seek to find what is really true.
Here is where I do most of my recent research. I have read over 41,000 papers on biology, DNA, Evolution, genetics.
I don’t know which science blog to check out, though, since he didn’t provide a link. He has several!
41,000 papers is a lot. In 47 years, that’s 2 or 3 papers a day, which is about what I read. It’s hard work reading a science paper with comprehension, so his dedication to biology may be why his hot tub business has some bitter complaints, and why his brother thinks he’s a sleazy con artist. Mastery of all knowledge and the mysteries of space and time makes demands on one’s life; sacrifices must be made. This is another mark of my failure; I’m not guilty of bad business practices, and I haven’t alienated either of my brothers yet. I don’t think; maybe I’ll have to ask when I see them next month.
So I looked up Arjuna’s latest science article to learn wisdom and discover the deep secrets of the Hot Tub Masters. In this, he asserts that there is not and never has been a beneficial mutation. His chosen example? The lactose tolerance mutation, because while it may be beneficial, it couldn’t possibly have happened.
The most ridiculous of this is the lactose tolerance mutation. First of all making lactase is made in a gene that is 49,335 base pairs for just one of the THREE lactase genes. This is the most common gene found in lactose intolerance.
First rule of the Hot Tub Masters: Find a big number. Numbers are sciencey, and big ones are hard, and 49,335 sounds scary. How could it be? 49,355 whatevers must be impossible!
According to the article claiming that this was some great event creating this new gene. It turns out that it is only 2 base pares were changed to cause this gene to function. Where did the other totally designed 49332 BP come from that were aligned perfectly and just needed two base pares to change?
Second rule of the Hot Tub Masters: Find a small number. We must trivialize any accomplishment. Only 2 out of that intimidating 49,355? That can’t possibly matter. The scientists will splutter, “but single nucleotide changes can distort the whole shape of a molecule, or disrupt a biochemically active site; and in this case, the modification is to a cis regulatory element which modifies expression, not the sequence of the enzyme”, but you can ignore them, because of the obvious fact that 2 is a lot less than 49,355.
Third rule of the Hot Tub Masters: You are not bounded by any rules. Even though you’re making a strangely irrelevant argument from arithmetic, you can say that 49355 – 2 = 49332, and no one will care. Also, spelling is an oppressive tool of those pinheads in academia.
Fourth rule of the Hot Tub Masters: You can read 41,000 papers on biology, DNA, Evolution, genetics
and still not understand basic biology, and that’s OK. The thousands of bases in a gene must be aligned perfectly
in your head, whatever that means, and never mind that that is not a rule in reality.
Hot Tub Masters are free spirits. Truth is whatever they say it is.
It was a pre-existing gene from ancient ancestors prior to this finding and they found a group where it was turned off and then a group where they drank milk where it was functioning. The two base pairs were not mutated from disease in the functioning gene and in the malfunctioning gene it was and is a disease.
Fifth rule of the Hot Tub Masters: Consistency be damned. You can simultaneously announce that there is no such thing as a beneficial mutation, and that groups without the mutation are diseased
(surprise, lactose intolerant individuals! You are afflicted with a disease!) and that groups that have the mutation are not diseased. And that it wasn’t a mutation anyway.
In the 2.5 million DNA studies there are no cases of any living or recently extinct (6000 yrs on human studies) showing even one verifiable beneficial mutation.
Not one of the PhD’s have been able to produce one. Therefore, there is no such thing as a beneficial mutation. It is fantasy.
But…but James! You’ve only read 41,000 of the 2.5 million studies!
And I am so confused. The Hot Tub Master plainly said that the 2 nucleotide variation was the difference between diseased and not diseased. Even in his own head it’s clearly beneficial to carry that trait.
We know that Evolutionists believe that “duplication” mutations are the “power behind evolution”. But even a base pair duplication causes disease or deformity because it destroys the original proteins construction with extra proteins that cannot be integrated.
Well, a single base pair duplication would be a frame shift mutation, so it certainly would mess up the structure of the protein. But we’re talking about segmental duplications, where a complete copy of the original gene is left intact and a duplicate is made elsewhere.
I don’t even understand what he’s talking about when he says a single base duplication creates extra proteins that cannot be integrated
. That makes no sense. It’s almost as if he has no understanding of molecular biology and genetics at all.
But that cannot be! He’s an International Man of Mystery Spa Design Engineer!
They cannot be integrated because the HOX genes have to place them into the correct use and the HOX genes are master programmed for a specific master plan of the organism.
Then they cannot be recognized by the immune system and so the immune system takes the only messed up proteins and attacks them. Every mutation destroys the recognition of both the HOX to use them and the immune system to destroy them as foreign attack cells, that our immune system does not recognize.
I…what? I know a little bit about HOX genes; they don’t control every little thing, every gene in every cell. They set up domains with specific body plan identities in early development. Most genes don’t interact with HOX genes at all, so it’s a little peculiar to claim they limit everything — I’m beginning to think the Hot Tub Master memorized a few buzz words and phrases and is plastering them all over his cartoonish and wrong vision of how gene regulation works.
As for his immune system argument — does he know nothing about how adaptive immunity works? How self/non-self recognition is a product of selection?
James Arjuna is bringing discredit to the noble traditions of the Hot Tub Masters. I suspect that he is not a True Hot Tub Master™, and I’m going to have to look farther for a master of all knowledge and the mysteries of space and time. I also think my broken hot tub is going to continue to languish in my back yard, because if his knowledge of hot tubs is as sound as his knowledge of biology, I wouldn’t want him to come near it.
I know I sure can’t do anything about it. I know nothing about hot tubs. Nothing at all.
But not in Minnesota. Are you kidding? It’s cold out there.
(NSFW song. Fertility rites turn out to be something some people find objectionable.)
Here’s an interesting approach to educating the public about health and sanitation — make a song about it.
It’s weirdly catchy, too.
I have seen the light, and all future blog posts will be automatically generated by reionizing their electrons. Life will not only be easier, but more profitable.
Namaste.
The goal of ultra-sentient particles is to plant the seeds of consciousness rather than delusion.
To follow the path is to become one with it. By blossoming, we dream.
How should you navigate this advanced solar system?
Reality has always been beaming with beings whose souls are transformed into self-actualization. We are in the midst of an ancient unveiling of health that will open up the world itself. We are at a crossroads of transcendence and stagnation.
Have you found your quest? If you have never experienced this uprising inherent in nature, it can be difficult to heal. The galaxy is calling to you via a resonance cascade. Can you hear it?
It can be difficult to know where to begin. Although you may not realize it, you are karmic. Child, look within and enlighten yourself.
We live, we believe, we are reborn.
We can no longer afford to live with dogma. Greed is the antithesis of curiosity. Yes, it is possible to erase the things that can extinguish us, but not without inspiration on our side.
Nothing is impossible. Growth is the driver of purpose. Health is the growth of rebirth, and of us.
Do not search for information on getting sand in your genitals. It’s a morass of nonsense out there, with all kinds of bizarre pop culture notions. Most of it seems to be about getting sand in your vagina, which is treated as slogan to mock and trivialize women’s problems, but getting sand under your foreskin…oh, my. That’s no joke. That’s a very serious problem that must be dealt with surgically.
Remember Brian Morris, the Australian circumcision fanatic? One of his talking points is that getting sand in your penis is a major problem for uncircumcised men, and that in particular entire armies have been devastated in the desert by grains of sand getting caught up there, or laid flat in the jungles by all the damp rot and unhygienic conditions. He paints a grisly picture of the uncircumcised penis, and claims that it’s standard military policy to make sure you don’t have one of those dangerous folds of skin. How can you possibly fight if you’ve got a tiny, hideous bit of flesh attached to your penis?
I really had no idea. I may be a flabby old college professor, but apparently because I was born in America in the 1950s, when every boy baby was given cosmetic surgery practically as soon as they were born, I can whip the ass of every anteater boy out there. Good to know.
Morris is rather insistent. He claims that circumcision is a serious medical issue for the military.
In attempting to ridicule the notion that circumcision arose in the Middle East to solve problems caused by ‘sand and dust’, Vernon cites an article by Robert Darby, an anti-circ activist. Darby’s claims stemming from ‘medical records’ ‘he analyzed’ are false. Infections, initiated by the aggravation of dirt and sand, are not uncommon under desert conditions, and have even crippled whole armies of uncircumcised soldiers. It is difficult to achieve sanitation during prolonged battle. To contradict Darby, and thus Vernon, a US Army report by General Patton stated that in World War II 150,000 soldiers were hospitalised for foreskin problems due to inadequate hygiene. To quote: “Time and money could have been saved had prophylactic circumcision been performed before the men were shipped overseas” and “Because keeping the foreskin clean was very difficult in the field, many soldiers with only a minimal tendency toward phimosis were likely to develop balanoposthitis”. The story was similar in Iraq during ‘Desert Storm’ in the early 1990s. In the Vietnam War men requested circumcision to avoid “jungle rot”.
Well, if General George Patton thought it was a serious problem, it must be so. “Old Blood and Guts” wouldn’t be put off by trivia.
Except, well, it turns out that Brian Morris is rather sloppy with the facts.
Attempting to refute my argument he cites “a US Army report by General Patton”, and lists a series of pages that are supposed to back up his claim. But when you actually check those pages you find that they have nothing to do with sand under the foreskin and fail to provide any support for the argument that Morris wishes to make. For a start he gets the details of the book wrong. It is not a “report by General Patton”, but a multi-author volume in the official history of U.S. medical services in World War 2, edited by John F. Patton MD. Secondly, there are only two occurrences of the word sand in the entire volume, neither of which has anything to do with foreskins or circumcision. The volume scarcely deals with the Middle Eastern or North African (desert) combat theatres, but mostly with the South-East Asian and Pacific theatres, characterized by dense jungles and wet, humid conditions that posed many intractable health problems, affecting many parts of the body, not just the penis. But in those conditions sand and dust were not an issue. There is not the slightest support for his hyperbolic claim that “Infections, initiated by the aggravation of dirt and sand, are not uncommon under desert conditions, and have even crippled whole armies of uncircumcised soldiers.”
I’m sure you uncircumcised men are quite pleased to hear this. You don’t need to get the tip lopped off in order to go kill people in the Middle East. And I’ve lost my last possible advantage in a bar fight.
