Death of science by multiple organ system failure

Science fairs usually have a few pleasant surprises, a lot of ho-hum projects done by rote with little thought (sometimes clearly done the night before), and a few stinkers that reveal nothing but the student’s ignorance. The science teachers are supposed to screen the project proposals to prevent that from happening, though, so the really bad projects usually don’t get through. There’s also a hierarchy: local to county or regional to state, and only the best are supposed to progress. State science fairs usually have some very impressive work and some that might be naive, but at least the student has enthusiasm. This description of a state level science fair project is disturbing, not just because the student’s work was substandard, but because it somehow made it through what should have been multiple levels of screening.

Then I saw it. “Creator or Not? YOU DECIDE”

The title claimed we could decide, but the project left no room for vacillation. It started with a hypothesis that “The universe was created by an intelligent designer.” It went on to make the standard big number argument, and closed with the conclusion, “The universe was created by an intelligent designer.”

The big number argument: there are twenty amino acids. The average human protein has around 460 amino acids in it. Thus the number of possible combinations is a huge number. The age of the universe in seconds likewise is a huge number, but less huge than the number of possible amino acid combinations. Thus you would have to have been randomly generating these protien chains at the rate of bunches every second from the Big Bang to now before you got human protein chains. Clearly that didn’t happen; therefore, an intelligent designer did it. Quod erat demonstratum.

That’s extremely distressing. It’s sad that some kid has such a poor knowledge of logic and evidence, but it is even more troubling that the educational system has rotted out so much that shoddy work like that can actually advance that far. We should worry about individuals, of course, but this is a sign that the educational infrastructure that leads to good scientists isn’t working—there was a complete failure from parents to science teacher to fair judges, and all of those people ought to be ashamed of themselves. This is not how we get kids into the Siemens Westinghouse competition.

(via The Scientific Activist)

Catfish eating its dinner

John Lynch beat me to this story about catfish feeding on land, so I’ll be brief. It shows how the eel catfish, Channallabes apus, can manage to take an aquatic feeding structure and use it to capture terrestrial meals. Many fish rely on suction feeding: gape the mouth widely and drop the pharyngeal floor, and the resulting increase in volume of the oral cavity just sucks in whatever is in front of the animal. That doesn’t work well at all in the air, of course—try putting your face a few inches in front of a hamburger, inhale abruptly, and see how close you come to sucking in your meal. So how does an aquatically adapted feeder make the transition to eating on land?

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Godless physiology?

The “neurotheologist” Michael Persinger is a fellow with an interesting idea: that the sensation of god is a product of activity in the brain. He induces activity in the brain with electromagnetic fields, and some people feel a sense of oneness with the universe or that aliens are peering over their shoulder.

Richard Dawkins is an infamous atheist who needs no introduction here.

Put the two together, have Persinger strap his electromagnetic helmet on Dawkins’ head and stimulate the temporal lobes, the apparent seat of spiritual sensation, and what happens?

Nothing.

Horizon introduced Dr Persinger to one of Britain’s most renowned atheists, Prof Richard Dawkins. He agreed to try his techniques on Dawkins to see if he could give him a moment of religious feeling. During a session that lasted 40 minutes, Dawkins found that the magnetic fields around his temporal lobes affected his breathing and his limbs. He did not find god.

I guess some people are more resistant to the god delusion than others, even when spirituality is injected directly into their brains on a wire. It makes me wish I could try this gadget out.

(via Amused Muse)

Sex in the MRI

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This morning I got a question in e-mail, asking if I’d heard of a particular paper. Of course I had, it’s a very fun bit of research…and then I realized I’d never mentioned it on the weblog before. I guess it’s because it’s focused entirely on the phylum Chordata, specifically one rather peculiar species—Homo sapiens. I probably just assumed nobody would be interested, because there aren’t any arthropods or molluscs in it.

The paper is all about visualizing the arrangement of organs during coitus. People have tried to figure out how the pieces all fit together internally using cadavers and their imagination, by using a speculum and poking around with their fingers, and by clever tools, like hollow glass tubes shaped like a penis. This paper tries something different: the investigators had people have sex in an MRI tube, and snapped a few pictures while they were at it.

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Complex biochemical systems slap Behe upside the head

Ian Musgrave does a wonderful job explaining the recent Science paper on the evolution of hormone binding sites. This is the work that Behe has called “piddling”, and claims that it has no relevance to the evolvability of complex biochemical systems. Ian takes this idea apart with a quick tour of the wandering goalposts of irreducible complexity:

Behe and the Discovery Insitute have reacted quickly and negatively to this paper. But in doing so they display a curious amnesia. Behe says:

I certainly would not classify their system as IC. The IC systems I discussed in Darwin’s Black Box contain multiple, active protein factors. Their “system”, on the other hand, consists of just a single protein and its ligand.”

Yet this “system” is precisely the thing that Behe uses in his exemplar for the Behe and Snoke paper, the binding of DPG to haemoglobin. And Behe has said in testimony to the Dover trial that the Behe and Snoke paper on evolution of binding sites is about irreducible complexity. So if the evolution of the DPG binding site (where you only need two mutations to make a functioning DPG binding site) is an example of IC, then the evolution of the aldosterone binding site is also.

Poor Behe. The man continues his ever-accelerating slide into the land of pathetic jokes.

RU486

After I summarized how Plan B contraception works, I’m still getting letters confusing it with RU486. RU486 induces abortions. Plan B does not. RU486 is the opposite of Plan B.

Remember that what Plan B is is an artificially high dose of progesterone (it actually uses a progesterone analog, but it’s effectively the same.) Progesterone is a hormone that maintains the uterine lining in a nice, rich, spongy, receptive state, and it also suppresses another hormone, LH, that is what triggers ovulation. Plan B keeps the uterus primed for implantation, but tells the ovary to hold its fire and not release an egg.

RU486 can’t get much different. It’s a compound, mifepristone, that antagonizes progesterone—it binds to progesterone receptors and blocks their function, so that it looks to the cells as if progesterone levels have all all dropped to zero. The cells of the uterus, whether implantation has occurred or not, are tricked into menstruating right away, shedding the uterine lining and anything growing in it.

Now I personally think RU486 is a fine idea and a perfectly reasonable and relatively safe way to induce an abortion, and I think it ought to be legal and available. However, it is nothing like Plan B. Plan B is a completely separate issue from any argument over the ethics or utility of abortion.

Where have I been?

It’s been a long day for me—I made yet another of those long drives into Minneapolis and back. It was worth it, though. We had the first meeting of a new group, Minnesota Citizens for Science Education; I think it’s going to be a useful resource for the state. It consists of several of us college professor types, plenty of K-12 educators, and a few business people, and we’re all going to be working together over the next few months to put together information to further the cause of good science teaching in Minnesota.

Details will have to wait, though. We’ll be aiming for a formal announcement in the Fall, with a public meeting on the topic at about the same time. Give us some time to get organized.

Isn’t it nice how crazy organizations like the Discovery Institute and Answers in Genesis are inspiring scientists and educators to get together and work to help our kids learn science better?

Why the wingnuts hate Plan B

There has been an oddly evasive struggle going on in Washington DC for the last several years. We have a safe, easy method of emergency contraception that has been turned into a political football, with Republicans playing their usual role of criminally stupid thugs, trying to crush a simple idea: Plan B contraception. It illustrates exactly how the Religious Right is trying to intrude on your private life, and in particular, how they want to control women.

I’ll explain how Plan B works, but to do so I’m going to have to explain some basics of the hormonal control of the menstrual cycle.

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