The height of anti-abortion logic

It’s been yet another long, long day — I was one of many invited speakers at a conference on Networks and Neighborhoods in Cyberspace at the Twin Cities branch campus of the University of Minnesota Morris, and I got to make an early morning drive there and a late afternoon drive back. Drive, drive, drive. It gets old. Especially on those mornings when it is -15°F (around -25°C for those of you who insist on more civilized measurements.) If you’ve seen the movie Fargo you know what the scenery is like: endless snow-covered fields, endless rows of posts for barbed-wire fences, a succession of teeny-tiny farm towns. There is one thing I watch for — and this is a measure of how boring the drive is — and that’s the anti-abortion signs.

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Let’s just go back to arranged marriages

This is probably a serious site. Probably. It could be satire, but the line between satire and Christianity is razor thin. Read Christian dating tips, and judge for yourself.

First rule of Christian dating: it’s pretty much like going to church. Boring, chaste, and offering nothing but faint hopes. No intimacy is allowed, not even a kiss.

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Stem cell breakthrough

Blogging on Peer-Reviewed Research

A recent discovery in stem cell research is no minor event: researchers have figured out how to reprogram adult cells into a state that is nearly indistinguishable from that of embryonic, pluripotent stem cells. This is huge news that promises to accelerate the pace of research in the field.

The problem has always been that cells exist in distinct states. A skin cell, for instance, has one set of genes essential for its specific function activated, and other sets of genes turned off; an egg cell has different patterns of gene activation and inactivation. Just taking the DNA from a skin cell and inserting it into the egg cell isn’t necessarily going to create a functional egg cell, because genes essential for egg cells may be switched off in the skin cell DNA, and we don’t know how to specifically switch them on. The process of somatic cell nuclear transfer has been hit or miss for that reason, with very high failure rates—scientists are basically trying to make the right configuration of genes switch on by giving the nucleus a good hard kick, and hoping that something in the cells will reconfigure the pattern of gene activation into something appropriate.

What the discovery by Takahashi et al. accomplishes is to reveal how to specifically switch on the right pattern of genes for a pluripotent stem cell. They have discovered the reset button for mammalian cells: a simple trigger that puts the cells in the right state to become anything else.

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Wake up, everyone!

A few little videos by way of the marvelous Kevin Hayden:

  • Ladies, did you know that you are just like a cardboard box? We’re supposed to treat you delicately and with respect, just in case you’ve got something in your uterus. If you’ve had a hysterectomy or you’re menstruating, though, and we know the box is empty, well, we don’t have to worry about you so much.

  • Guys, did you know that you are followed everywhere by a mob of enthusiastic, hyperactive sperm? I love how both sexes can be objectified by the functions of our gonads.

  • I’ve shown the video for this one before, but I’m going to do it again just because I love the New York Dolls and this will put you in a happy mood for a Monday morning. Here are the New York Dolls performing “Dance Like a Monkey” live:

The nadir of Howie Mandel’s career?

No way — I’ve seen Gas and Little Monsters, so this review of his sex ed movie, Where did I come from? gets that part wrong. I think the video and the book Where did I come from? aren’t actually that bad; it’s cutesy, it doesn’t take the whole ridiculous business too seriously, and it gets the job of telling the kids the essentials done without too much fuss. If you can find it and have a young kid who needs to have sex explained, it’s worth watching together.

If they’re much beyond 8, though, don’t bother. They always know more than you think.

Those Catholics in Canada have been acting up lately, haven’t they?

Now the Catholic schools want to ban the HPV vaccine. I simply do not understand that attitude. I can understand wanting to protect your daughter from the entanglements and risks of too-young sex, but this is a vaccine to protect them 1) from a disease 2) transmitted by sex. My eyes tend to focus more on point 1 than on point 2; 1 has greater penalties and none of the joys of 2, and protecting against 1 does not entail that 2 will occur.

Is there something in those communion crackers that shorts out the logic circuits of the brain?

Male pregnancy?

Yesterday’s discussion of future biological advances that will piss off the religious right had me thinking about other innovations that I expect will happen within a few decades that might just cause wingnuts to freak out. First thing to come to mind is that it will be something to do with reproduction, of course, and it will scramble gender roles and expectations…so, how about modifying men to bear children? It sounds feasible to me. Zygotes are aggressive little parasites that will implant just about anywhere in the coelom — it’s why ectopic pregnancies are a serious problem — so all we need to do there is culture a bit of highly vascularized tissue in the male abdomen that will serve as a secure home for a few months. We’ll have to play some endocrine games, too, which may effect his love life but will also prepare him to lactate post-partum. There’s the minor anatomical problem that the vagina is a unique tissue, and no, the urethra is not homologous or analogous (fortunately; we wouldn’t want to have to push an 8 pound baby through the penis, even if female hyenas can manage it) — but that’s what c-sections are for. Given money, time, and a few weird volunteers, it could be done.

The next question is, has it been done? Are there any other vertebrates that have males doing the hard work of pregnancy? There were the gastric brooding frogs, which one would think could have made the leap easily — the eggs were just swallowed and developed in the stomach — but only the mothers seemed to have done the job. They’re all extinct, anyway. Male frogs of the genus Rhinoderma brood their young in their mouths, but this is after external fertilization and development, so they’re actually simply holding larvae in a safe place — and they’re also endangered. The precedents aren’t promising.

There is an extremely interesting and successful example, though: the syngnathid fishes, sea horses and pipefish. In all 232 species, the female lays her eggs in a specialized male structure called the brood pouch, where they are fertilized and develop. It’s a true male pregnancy!

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