A little good news

The Trump administration and his unelected stooge, Elon Musk, had charged in and imposed a blanket reduction of all indirect costs to 15% — indirect costs are the mechanism used to support the infrastructure of science all across the country. This was a devastating, crippling strike against research.

Not so fast, says a judge.

A federal judge in Boston ordered a nationwide temporary pause on plans by the National Institutes of Health to substantially slash research overhead payments to universities, medical centers, and other grant recipients.

Judge Angel Kelley of the U.S. District Court for the District of Massachusetts issued the temporary restraining order late Monday night in response to a lawsuit filed that afternoon by associations representing the nation’s medical, pharmacy, and public health schools, as well as Boston and New York-area hospitals. The suit names the NIH, Department of Health and Human Services, and the acting heads of both agencies as defendants.

In the order, Kelley wrote that the defendants cannot take “any steps to implement, apply, or enforce the [policy] … in any form with respect to institutions nationwide until further order is issued by this Court.”

That’s good. Unfortunately, I don’t like the idea of judges deciding the fate of universities, because if one thing is clear, there is no objective standard in how laws are applied, especially since different judges are expressing different opinions, and the judiciary is already packed with ideologues. Thanks, Federalist Society!

Perhaps more encouraging is that some Republicans are waking up to the fact that they’re getting boned by Trump policies.

Red-state universities are hitting back at the Trump administration’s expansive cuts to science and research funding, warning they would be forced to shutter laboratories and lay off staff should they face the sudden elimination of millions of dollars in funding.

The blowback, echoed by at least two Republican senators, marks the most widespread political resistance the Trump administration has faced in its rapid sprint to reshape the federal government and its spending policies.

There are very good universities imbedded in all those red states — they provide resources and training that are essential to the economic well-being of those regions. Even Republicans know this, and they have begun stirring to defend against the Trump/Musk idiocy.

Universities in conservative strongholds have spent the last few days warning of the drastic economic and scientific toll of the new funding limit, putting fresh pressure on Republican officials to stand up for their states. The episode could also amplify scrutiny of Trump’s pick to run the Education Department, Linda McMahon, ahead of her confirmation hearing on Thursday.

Sen. Susan Collins (R-Maine) slammed the policy as “devastating” and illegal.

Oh fuck no…Susan Collins is saying she opposes it? You know what that means: as soon as an opportunity to act rises up, she’s going to vote for anything Trump says. That’s the problem: you can convince Republicans that something is against their self-interest, but when push comes to shove, they’ll align themselves with the biggest bully in the room.

Is your state on this list?

These are the states suing HHS and the NIH over their disastrous policy on indirect costs.

COMMONWEALTH OF
MASSACHUSETTS, ATTORNEY
GENERAL DANA NESSEL ON BEHALF
OF THE PEOPLE OF THE STATE OF
MICHIGAN, STATE OF ILLINOIS,
STATE OF ARIZONA, STATE OF
CALIFORNIA, STATE OF
CONNECTICUT, STATE OF
COLORADO, STATE OF DELAWARE,
STATE OF HAWAI’I, STATE OF
MAINE, STATE OF MARYLAND,
STATE OF MINNESOTA, STATE OF
NEW JERSEY, STATE OF NEW YORK,
STATE OF NEVADA, STATE OF NEW
MEXICO, STATE OF NORTH
CAROLINA, STATE OF OREGON,
STATE OF RHODE ISLAND, STATE OF
VERMONT, STATE OF WASHINGTON,
and STATE OF WISCONSIN

I’m looking sideways at the states not on the list. I can understand the fascist states of Florida and Texas not joining in, and all the bible belt states, but what’s wrong with you, Pennsylvania?

Good for you if you live in the listed states, otherwise, get to work and vote the rascals out.

Another memo from the UM president

At least we’re getting words of encouragement from the administration.

Dear Colleagues,

Since our founding in 1851, the University of Minnesota has distinguished itself as a global leader in research, scholarship and creative practice.

From pioneering the first open heart surgery to unlocking the secrets of DNA repair, our students, faculty and staff have always maintained an unwavering commitment to serving the world through discovery and innovation.

Thank you for everything you do.

The federal government’s recent notice calling for a 15 percent indirect cost rate on all new awards from the National Institutes of Health is a direct attack on our ability to advance the University’s public service mission, and it has created fear and uncertainty across our community. This decision would cut reimbursements for research facilities and administrative costs, which cover critical, lifesaving research activities ranging from patient safety to research security. It would no doubt have serious consequences for patients across the state, as well as our students, faculty and staff.

According to Mark Becker, President of the Association of Public and Land-grant Universities, “NIH slashing the reimbursement of research costs will slow and limit medical breakthroughs that cure cancer and address chronic diseases such as diabetes and heart disease. Let there be no mistake: this is a direct and massive cut to lifesaving medical research.”

As a principal investigator on numerous NIH grants throughout my career, I understand how devastating this announcement must be for many members of our community.

University leaders convened over the weekend to chart a path forward, and we are actively partnering with higher education associations and peer institutions across the country to identify ways in which we can effectively address this rapidly evolving situation head on. With guidance and support from our Government and Community Relations Team, we have implemented a broad outreach strategy to ensure that members of our federal and state delegation fully appreciate the profound implications of this notice.

We are also supporting national efforts led by higher education associations to address the legality of this directive, and the University will stand in firm opposition to such drastic cuts that impede on our ability to advance research discoveries and innovations.

My leadership team and I will remain fully engaged on this issue, as well as other federal policy changes that affect our community and impact our operations. I recognize that news of this notice creates a significant level of fear, uncertainty and concern.

Please know that I am committed to ensuring our University’s primary missions of teaching, research and outreach thrive. And I will continue to advocate on your behalf, as the University explores every avenue to aggressively address the challenges posed by this notice.

We are one of America’s leading public research universities, and I will loudly champion the work of our students, faculty and staff so they can continue to advance research, scholarship and creative practice for the betterment of our society.

If you have any questions or concerns regarding the latest announcement from NIH, please contact our Research and Innovation Office at rio@umn.edu, or connect with a research administrator in your school, college or unit. I also would encourage you to visit z.umn.edu/fed-impacts for research-related updates and FAQs.

Sincerely,

Rebecca Cunningham
President

Also, note that the University of Minnesota Morris will keep on celebrating Black History Month no matter how nasty the White House gets.

Microbiologists, hang your head in shame (or fight back!)

Shame on the American Society for Microbiology.

A prominent US scientific society altered its website to remove references to diversity and equity ― terms targeted by the administration of US President Donald Trump. Articles about scientists who are members of under-represented groups also temporarily vanished from the site, although they have since reappeared.

The editing sparked an outcry among some of the more than 37,000 members of the organization, the American Society for Microbiology (ASM) in Washington DC. Some ASM members note that other scientific societies have posted statements in support of diversity, equity and inclusion (DEI), rather than deleting terms targeted by White House orders.

Their excuse? They were just following the orders of their lawyers.

That sounds familiar, for some reason.

Read about Chemistry in Nazi Germany. The major scientific societies in Nazi Germany were quick to pander to Hitler, and they had the same kinds of arguments: they were patriots supporting their country, they had to fire all those Jewish professors to keep government support, etc., etc., all while they were looting conquered nations and doing secret work on nerve gasses and sieg heiling their way to bigger grants.

“It is one of the most notable phenomena in academia in 1933 that the severest measures of National Socialist policies against science were carried out under a high degree of silence and with the frequent consensus of scientists,” writes Deichmann in a review of chemistry during the Nazi era (Angew. Chem. Int. Ed.2002,41, 1310). She has found only a single instance in which a German scientist refused to accept a new position created through the dismissal of a Jewish scientist.

This silence regarding the unfair dismissal of Jewish colleagues was common across most fields of science, and it stemmed from some combination of anti-Semitism, nationalism, cowardice, obedience, or opportunism, Deichmann says. The vacant positions were often taken by young scientists who may not have had comparable academic career opportunities had anti-Jewish policies not cleared the way. Perhaps for this reason, Deichmann notes, 63% of young scientists joined the Nazi Party, a larger percentage than the 53% of chemists and biochemists of all ages who joined.

The article is specifically about chemistry, but to be fair, all the disciplines were doing it. Hans Spemann, the Nobel-prize winning development biologist, was busy coordinating the purge of Jewish scientists from German universities.

What chemists did was mirrored in the rest of Germany’s scientific community. “Chemists received a lot of support for their research” from the Nazi regime, Deichmann says. “But I am not sure we can say they were more opportunistic than other” scientists. Comparable percentages of biologists, psychologists, and chemists joined the Nazi Party, she says. The German Biological Society, for example, had a journal called Der Biologe (The Biologist) that was entirely full of Nazi ideology, and psychologists and biologists participated in terrible human experiments, she adds.

After the war, these same scientists were quick to say “I knew nothing!” and pretend to have been oppressed by the Nazis.

After the war ended and international scientists began asking pointed questions about the activities of their German colleagues, Maier says, German researchers increasingly adopted a false narrative that they had suffered under Hitler, despite their flush funding under the Third Reich. “They would say the Nazis were anti-intellectual, antiscientific, and anti-basic research,” he says. “This is absolutely false.” The Third Reich “was a paradise for these scientists, compared to the situation up to 1933, when there were many cutbacks” because of financial constraints imposed by the terms of the Treaty of Versailles, which ended World War I.

Many chemists claimed they didn’t know what had been happening at Ausch­witz’ Monowitz-Buna factory and at other concentration camps. “But how can you get such a large chemical factory established and running smoothly without any chemists present?” Maier asks. Kuhn, for instance, may not have personally visited any concentration camps, but as director of the Kaiser Wilhelm Institute for Medical Research and president of DChG throughout the war, he was certainly privy to some aspects of Hitler’s human experimentation, Deichmann notes.

I wish I could say that Richard Kuhn received his comeuppance after the war, but no. He had been an active supporter of the Nazis, ratting out his Jewish colleagues and promoting Nazi dogma.

From the beginning of the Third Reich, Kuhn also began to pepper his speeches at home and abroad with “Sieg Heil,” even at non-Nazi functions. When he won the Nobel Prize in 1938 for his natural product research, Kuhn rejected the prize with a letter punctuated with his handwritten addendum: “The Führer’s will is our belief.” During the war, Kuhn also did extensive research on the toxic nerve gases tabun and sarin and invented a poison gas called soman.

Once the war was over, he happily accepted his deferred Nobel prize (I guess the Füher’s will was inoperative after he blew out his brains) and got a bland, boring writeup on the Nobel foundation site. Perhaps the only recognition of his heinous behavior was that a scientific prize in his name, the Richard Kuhn Medal, was discontinued in 2005, long after his death in 1967.

In 2005, the Society of German Chemists (Gesellschaft Deutscher Chemiker, GDCh) declared their intention to no longer award the Richard Kuhn Medal: “The board of the GDCh intends to discontinue awarding the Medal named after the organic chemist, Nobel Prize laureate of the year 1938 and President of the GDCh in 1964–65, Richard Kuhn. The board thereby draws the consequences out of research on Richard Kuhn’s behaviour during National Socialism. Even though the question of whether Kuhn was a convinced National Socialist or just a career-oriented camp follower is not fully answered, he undisputably supported the Nazi-regime in administrative and organizational ways, especially by his scientific work. Despite his scientific achievements, Kuhn is not suitable to serve as a role model, and eponym for an important award, mainly due to his unreflected research on poison gas, but also due to his conduct towards Jewish colleagues.”

We can’t even threaten the chickenshit administrators at ASM with posthumous ignominy, I guess. Even Richard Kuhn gets the benefit of the doubt about whether he was actually a Nazi, so I guess even minor functionaries who bow down before Trump are safe from public shaming.

All we can do is suggest that maybe they should consider doing what is right.

Like the Minnesota State High School League, which has shown more courage than the well-educated chickenshits at the ASM.

The Minnesota State High School League will continue its policy of letting student-athletes “participate consistent with their gender identity,” according to a memo sent to MSHSL member schools on Thursday.

The MSHSL’s message came a day after President Donald Trump signed an executive order seeking to ban transgender athletes from participating in women’s and girls’ sports.

“The Minnesota State High School League, similar to other youth sports organizations, is subject to state anti-discrimination laws, which prohibit discrimination based on gender identity,” the MSHSL said. “Therefore, students in Minnesota are allowed to participate consistent with their gender identity.”

In 2023, the state Legislature amended the Minnesota Human Rights Act to include gender identity as a protected class shielded from discrimination in areas such as employment, housing and education.

Resist in every little way you can.

When an idiot is in charge of science’s purse strings…

Here’s a fantasy for you: a rich man uses his immense wealth to alleviate poverty, fund science that benefits all, or decides to distribute all of his money to worthy institutions. It never happens. Instead, we get the world’s richest man using his clout to get a job he isn’t qualified to do, who then uses his unwarranted power to do the opposite, and kill the research enterprise of the United States with one stupid stroke of his pen.

I’m not being dramatic. US research is the product of years of investment. There was a conscious decision to build up a more effective program of research and development after WWII, built upon the existing foundation of expertise in our universities (thanks, Vannevar Bush!). The government knew it would take long-term training and money and resources to create, and part of that was a system of federal grants to researchers with additional funds to the research institutions to build and maintain their infrastructure, which are called indirect costs. You don’t get anything for free! You want to encourage biologists to study the genome, well, you’re going to have to ask a university to maintain a large animal care facility, and hire people to keep an eye on the ethics of such research, and hire accountants to manage the expenses, and veterinarians to keep the animals healthy, and secretaries to help write up the work, and you’re going to have to pay publishers to disseminate it. It’s not cheap.

It’s true that there is some administrative bloat — Harvard is filthy rich, and I think they’ve been gaming the system to inflate those indirect costs — and the article at the link points out that there are a lot of regulations that could be streamlined, but to do that streamlining in a way that retains the useful necessities requires detailed analysis and careful pruning. Only an idiot would think you can just slash all indirect costs to the bone in one crude, extreme cut without totally disrupting all research at American universities.

Enter the idiot.

Musk doesn’t have the slightest clue what he is doing.

Yes, he is cutting funding for cancer research. He’s imposing a blanket, indiscriminate cut for all research. He’s going to gut a whole generation of scientists, a wound it would take decades to recover from, if there was any recovery possible. I suspect that instead of repair what’s going to happen is we’re going to replace universities with bible colleges, pandering to the populist idea that we can pray cancer away.

It required a coward to be this petty

A scene in an FBI building: the walls that were covered with words reflecting virtuous concepts were painted gray.

What I find depressing is picturing the thought that went on behind this action. Someone somewhere in the hierarchy thought it was a good idea to pass down an order to erase words like “fairness,” “leadership,” “compassion,” “integrity,” etc., all in order to wipe out the word “diversity.” No one stood up and said that this was silly and pointless and a waste of time and offensive.

Maybe no one at the FBI has a spine.

Perhaps it was appropriate that they erased the words “leadership” and “integrity.”

How to kill American science

Trump, Musk, and RFK jr are a horrific combo that has discovered how fragile the institution of science can be — all it takes is handing the keys to funding to a small number of incompetents and ideologs. It’s such a simple thing: decree that a few words are verboten and will get your grant application pulled. Take a look at the complete list of words that will flag a grant for being held. They include “gender,” “disability,” and “race”. They include “female” and “women,” but not “male” or “man”. They include “socioeconomic,” “socio economic,” and “sociocultural”…they really wanted to make sure that they got that one covered.

The NSF has sent out this ridiculous decision tree:

Seriously. You want to know how these bad decisions are sailing through? It’s because there is a petty bureaucracy running the NSF that designs redundant, pointless, stupid diagrams like that. It’s Kafkaesque.

The USC professor who is reporting this says:

These keywords could show up in the text of ANY grant involving human participants. If you say you’re going to study men and women, you get flagged. If you say you’re going to control for socioeconomic status – totally standard practice – you get flagged. Disability? Flagged.

The word “systemic” is on the banned list, so if I study systemic inflammation & health, flagged. If I study political science, flagged. If I study trauma, flagged. Keep in mind that the largest mental health provider in the country is the Veteran’s Administration, but we can’t study trauma now?

If I study anxiety via threat-biased attention, the word “biased” gets me flagged. You can’t design a study of humans without using at least one of the terms on the banned list, which means that biomedical, brain, social science research is now on ice in the USA

And then, all the Republicans in congress have predictably caved and are going to approve a manifest madman, “Bobby” as they call him, to control health and human services, while a narcissistic boob, Elon Musk, is running rampant through the country’s finances.

So what next? All political norms have been shredded. Democracy doesn’t matter. Anarchy reigns. The law is irrelevant — do you think the Supreme Court can bring reason back? We’re all helpless, and are reduced to spectators to our rapid, catastrophic destruction. It’s going to get much worse.

Is the only solution a violent overthrow of the Trump regime, a complete dissolution of all of the Trump precedents, and a rewriting of the US Constitution? We have to recognize that the US is broken.

Scientific censorship is here

It has long been a desire by the Republicans to meddle in science — let’s filter out the results we don’t like. Nature reports that their desire has been made manifest: US health agency seeks to cut gender-related terms from scientific papers.

The US Centers for Disease Control and Prevention (CDC) has mandated that all scientific manuscripts produced by its researchers that are under review at a journal be withdrawn so that certain language relating to gender can be stripped from them.

The directive, sent by the agency’s chief science officer to some staff members on 31 January, is meant to bring the CDC into compliance with an executive order issued last month by US President Donald Trump seeking to restore “biological truth” to the federal government by recognizing only two sexes: male and female. Executive orders can direct agencies inside the federal government but cannot change existing laws.

According to a copy of the e-mail, shared in the newsletter Inside Medicine, manuscripts must not include any mention of terms including ‘gender’, ‘transgender’, ‘pregnant person’, ‘transsexual’ and ‘non-binary’, among others. CDC scientists who co-author papers originating from outside the agency that include these terms are also expected to rescind their authorship.

It’s all very Orwellian. They will dictate what words we’re allowed to use, because they believe that they can bend reality to conform. It doesn’t work that way, though. They’re just going to silence scientists who know better.

The CDC mandate, however, erases mention of queer, intersex and transgender individuals from future literature and seems to legitimize “scientific sexism”, says James Mungin, a biomedical scientist at the Tuskegee Institute in Alabama, who identifies as transgender. Under the new rules, CDC researchers would be unable to share basic demographic data, such as gender identity or sexual orientation, about study participants — omissions that could lead to inaccuracies or ethical breaches if scientists are barred from disclosing why certain participants were removed from a study, Mungin says. Furthermore, gender identity and sexual orientation are nearly impossible to exclude when it comes to the study and treatment of conditions such as HIV or other sexually transmitted diseases, potentially causing harm to patients.

“If you’re working in basic science, you might get away with just references to sex, but gender is everywhere in public health,” says Ayden Scheim, a social epidemiologist at Drexel University in Philadelphia, Pennsylvania, who identifies as trans and studies the health care of marginalized communities. “Unfortunately, I see two things happening: a lot of these withdrawn papers will never be published” because collaborators outside the CDC aren’t going to agree to omit data, Scheim says, “and in the long term, a lot of research that focuses on health inequities for women or LGBTQ+ people will disappear”.

There were a lot of scientists and lay people who threw around terms like “cancel culture” and “censorship” before Trump took office. Where are they now? They were so touchy about criticism or a refusal to platform bad ideas, but I don’t see them even acknowledging that these are actions well beyond anything that has gone before.

If we let them get away with censoring “gay” and “transgender,” what will we do when “climate change” is forbidden, or “evolution”?

Or “Jew”?