It should be no surprise that placing an anti-vaxxer and conspiracy nut in charge of the department of Health and Human Services, the cabinet office that oversees almost all the science and public health agencies in the US, was going to do serious harm. And sure enough, he is wreaking havoc.
One of the more disturbing things he has done is cancel a long-running diabetes study that was looking at the effectiveness of a medication known as metformin. The group that got this medication was compared with another group that got a placebo and a third group that made lifestyle changes to meet health goals, such as to exercise more and lose weight.
The study found that, in people with prediabetes, metformin lowered the risk of diabetes by roughly a third; the life-style intervention cut the risk by more than half. Both components were so successful that the trial was stopped early.
But the The Diabetes Prevention Program Outcomes Study had planned to continue the study to explore other important questions, using the participants that had been enrolled in the earlier phase.
How long do the health benefits last? How do blood-sugar levels affect the body and the brain over time? For more than a quarter of a century, Nathan and his colleagues tracked thousands of patients—which was itself a feat of logistical and scientific endurance.(Many doctors struggle to get their patients to attend annual physicals, let alone engage them for a study of this duration.)
