Another review of Behe’s book, The Edge of Evolution, has been published, this time in Nature and by Ken Miller. This one focuses on Behe’s central claim, that he has identified a probabilistic limit to what evolution can do that means no differences above roughly the genus level (and in many cases, the species level) can be generated by natural mechanisms. This is his CCC metric, or the probability of evolving something equivalent to the “chloroquine complexity cluster”, which he claims is the odds of evolving two specific amino acid changes in a protein. It’s a number he pegs at 1 in 1020, right at the edge of what a large population of protists can do, but beyond the reach of what a smaller population of slowly reproducing metazoans, like hominids, could hope to accomplish even with geological time limits. It’s the same problem I addressed in my earlier criticism, although Miller manages to slap it down with much greater brevity.

