Another good article on sociogenomics

Do you want to know how sociogenomics works? Here you go.

If this is “the science,” the science is weird. We’re used to thinking of science as incrementally seeking causal explanations for natural phenomena by testing a series of hypotheses. Just as important, good science tries as hard as it can to disprove the working hypotheses.

Sociogenomics has no experiments, no null hypotheses to accept or reject, no deductions from the data to general principles. Nor is it a historical science, like geology or evolutionary biology, that draws on a long-running record for evidence.

Sociogenomics is inductive rather than deductive. Data is collected first, without a prior hypothesis, from longitudinal studies like the Framingham Heart Study, twin studies, and other sources of information—such as direct-to-consumer DNA companies like 23andMe that collect biographical and biometric as well as genetic data on all their clients.

Algorithms then chew up the data and spit out correlations between the trait of interest and tiny variations in the DNA, called SNPs (for single-­nucleotide polymorphisms). Finally, sociogenomicists do the thing most scientists do at the outset: they draw inferences and make predictions, primarily about an individual’s future behavior.

Sociogenomics is not concerned with causation in the sense that most of us think of it, but with correlation. The DNA data often comes in the form of genome-wide association studies (GWASs), a means of comparing genomes and linking variations of SNPs. Sociogenomics algorithms ask: are there patterns of SNPs that correlate with a trait, be it high intelligence or homosexuality or a love of gambling?

Yes—almost always. The number of possible combinations of SNPs is so large that finding associations with any given trait is practically inevitable.

I’m not just being mean when I say it’s garbage science. “Chewing up data and spitting out correlations,” especially when correlations are ubiquitous, is not a productive approach to much of anything.

Where will it take us? That’s easy to see.

Advocates of sociogenomics envision a prospect that not everyone will find entirely benevolent: health “report cards,” based on your genome and handed out at birth, that predict your risk of various diseases and propensity for different behaviors. In the new social sciences, sociologists will examine the genetic component of educational attainment and wealth, while economists will envision genetic “risk scores” for spending, saving, and investment behavior.

Without strong regulation, these scores could be used in school and job applications and in calculating health insurance premiums. Your genome is the ultimate preexisting condition.

There’s precedent. The article mentions how Simon Binet invented the IQ test as a tool to identify and help students who were lagging in school…and then within decades discovered “that people were being sterilized for scoring too low”. I know that if I’d been assigned a genetic “risk score” with my family history, I and my brothers and sisters would have been doing manual labor for our short lives.

Also, I still want to know how this pseudonymous eugenics research program with it’s 15 new hires of “young, often charismatic scientists” is getting funded. Following the money would be a good idea here.

What the heck is sociogenomics?

I was asked recently about “sociogenomics,” and I had to stop and think because I was unfamiliar with the word. At a guess, I thought it would about looking for correlations between genes and socioeconomic groups, ethnicities, and races using tools like genome wide association studies and polygenic scores — you know, Bell Curve shit. To me, it sounded ominous and catastrophically bad, something that would shift into plain old eugenics and evolve into Nazi shit. But what do I know? I had to go look it up. I was just guessing.

Guess what? I guessed right.

Sociogenome is the comprehensive study of the role of genes and gene-environment (GxE) interaction on reproductive behaviour. Until now, social science research has focussed on socio-environmental explanations, largely neglecting the role of genes.

Drawing from recent unprecedented advances in molecular genetics we examine whether there is a genetic component to reproductive outcomes, including age at first birth, number of children and infertility and their interaction with the social environment.

Uh-oh. They’re just going to take modern genetic techniques and apply them to sociology. But these techniques will not give them the answers they want! They’ll reveal rough correlations, but they won’t untangle genetics and environmental factors — they can’t. This is a problem that has been pointed out to behavioral genetics researchers for years, and they just go sailing on ahead.

In the past decade and a half, sociologists and demographers have sought to integrate genetic data into their empirical analyses. To do so, they have drawn on recently developed high-throughput sequencing and genotyping technologies, which allow the entire genome to be mapped. They also follow in the line of a research specialty, behavioural genetics, which rose to prominence in the 1970s. This area, which focused notably on the genetic determination of intelligence, attracted severe criticisms, including among demographers (Jacquard, 1978; Vetta and Courgeau, 2003; Courgeau, 2017). However, these criticisms do not always seem to have been heard, and the emergence of new data and techniques has given rise to new problems, as indicated by calls for caution from learned societies in human genetics (Société française de génétique humaine, 2010; Risch, 2016; Société française de génétique humaine, 2018).

Let’s look at an example of a sociogenomics study that was summarized in Wired. It does not reassure me.

The UK BioBank is the single largest public genetic repository in the world, with samples of the genetic blueprints of half a million Brits standing by for scientific study. But when David Hill, a statistical geneticist at the University of Edinburgh, went poring through that data, he wasn’t looking for a cure for cancer or deeper insights into the biology of aging. Nothing like that. He was trying to figure out why some people make more money than others.

I hadn’t thought of that. They’re going to tap into modern behavioral databases, like all that information Facebook has about you, in addition to biological databases, and they’re going to try to weave the two of them into some kind of story. I’ve never been impressed by that.

Along with a team of European collaborators, Hill sifted through the UK Biobank data to find about 286,000 participants who had answered a survey question about household income. Using that information they conducted something called a Genome Wide Association Study, where they looked at 18 million places in the genome to see which ones matched up with higher paychecks. They uncovered about 30, which account for 7.4 percent of household income variation across the United Kingdom. (For some context, another way of viewing the results is to say that 92.6 percent of a person’s income is explained by factors other than genetics.) Hill noticed that many of the genetic differences overlapped with areas known to be associated with intelligence, based on some of his prior work, and when he mapped them out they were largely expressed in the brain.

His team then used these regions to compute a polygenic score, a genetic calculation that predicts a person’s odds of reaching a certain outcome—of, say, developing diabetes or earning six figures. It didn’t perform particularly well, correctly forecasting only 2.5 percent of the differences in income in an independent sample of Scots. “Your DNA will not print you money,” says Hill. But he’s relieved to have found some small effect. “If you’re born with a predisposi­tion for certain traits or abilities, and none of them counted in any way, shape, or form towards your income, then you’d have a profoundly unfair society, in my opinion,” he says.

Thanks, I hate it. So he started with the information about a quarter of a million people, went fishing for any correlation at all, and found a tiny percentage of the genetic variation might account for a tiny fraction of the variation in income, because of course they’re zeroing in on money. It looks like noise to me; I’d want to know haw they accounted for the fact that a great deal of wealth is inherited, so you’d expect to see some common traits threaded through lines of wealth. Trust fund babies are going to share genes with mommy and daddy, even if they have nothing to do with the source of their money.

Further, even their weak correlation hasn’t found a genetic basis for wealth. Genes aren’t pure entities that can be isolated in this way and tied to phenotype — everything is polygenic and pleiotropic, and absolutely dependent on the environment for their expression. No wonder I didn’t know what sociogenomics is — if I encountered it in a science journal, I’d glance at the abstract, gag, and turn the page.

Then I figured it out: sociogenomics is nothing but the new label slapped on Kathryn Paige Harden’s behavioral genetics, which I figured out a long time ago was garbage science. Here’s a solid critique of Harden’s ideas.

In her recent sociogenomics manifesto The Genetic Lottery, Kathryn Paige Harden sets out to rescue behavior genetics from the spectres of racism and eugenics. Sociogenomics, like behavior genetics, studies the possible role of genes in explaining complex human social behaviors. Critics have charged this area of study with fueling biological determinist theories of human social inequality.

Harden purports to offer a refreshing take on this old debate because she claims that such critics are blind to the role that genetics play in the very thing they aim to secure: social equality. She argues that, in fact, we must use genetic information to promote truly egalitarian social policy. Styling herself after 20th century anti-racist geneticists such as Theodosius Dobzhansky, Harden offers the new sociogenomics as an explicitly anti-eugenic synthesis of genetics and equality.

Harden is right that the legacies of eugenics haunt behavior genetics. The field’s findings have been used to argue that biological differences between social groups explain social inequality and to undermine the possibility of egalitarian interventions. Human behavior genetics and its successor, sociogenomics, have thrived on controversy about the alleged biological relationship between race and IQ and the alleged futility of educational interventions in closing achievement gaps. Harden’s particular focus—the notion that biology can explain population differences in educational attainment and cognitive performance—has been a pillar of eugenic discourse and white supremacist ideology. But Harden believes that it is possible to “[reclaim] genetic science from the legacy of eugenics, realigning it with egalitarian aims.” Harden’s “new synthesis,” she argues, is not only different from eugenics, but self-consciously anti-eugenic.

Harden draws an analogy between her critics’ “genome blindness” (her term for the failure to “see” genetic causes) and color blindness (the failure to “see” race). Just as color blindness undermines antiracism because it fails to grapple with the effects of racism, Harden argues that genome-blindness threatens egalitarian aims because it fails to grapple with genetic causes of inequality. But this analogy breaks down when the entanglement of behavior genetics with eugenics is taken seriously. Resisting eugenics depends on an understanding not of how genes work, but of how eugenics works. Anti-eugenic science demands an expansive and nuanced understanding of how eugenic thought developed. In this essay, we show that Harden’s account of eugenics seriously undermines her claim to rescue behavior genetics from its clutches.

Yeah. Harden is really unconvincing. Somehow, while claiming to be an anti-eugenicist, she embraces the modern genetic determinists and spurns the people who have been showing for decades that genes and environment are inseparable.

Harden’s failure to engage with critics of behavioral genetics, often from the political left, veers between simple omissions and outright misrepresentation. This treatment is in stark contrast to how she treats biological determinists on the political right. The work of Charles Murray, the co-author of The Bell Curve, which claimed that differences in IQ scores between the rich and poor were genetic, and whose research aligns neatly with Harden’s, is described as mostly true and his political implications are lightly challenged. The most prominent critic of behavioral genetics, Richard Lewontin, gets much rougher treatment.

In one of the three cases in which Harden bothers to mention Lewontin’s decades-long engagement with behavioral genetics, she gets it wrong, claiming that Lewontin merely said that heritability is useless because it is specific to a particular population at a particular time. In reality, Lewontin showed why the statistical foundation of heritability analyses means it is unable to truly separate genetic and environmental effects. Contra Harden’s characterization of her opponents, Lewontin recognized genetic factors as a cause of phenotypes; however, he stressed their effects cannot be independent of environmental factors and the dynamics of development.

Called it. Told you this was going to be some Bell Curve shit.

What really clinches for me that this is something more than a few fringe scholars coming up with fancy titles for the junk science they are doing, though, is this surprise. Purdue is making a massive investment in creating a sociogenomics department from scratch.

Together the College of Liberal Arts and the College of Science at Purdue University seek applications for multiple scholars in Sociogenomics, including existing groups of investigators, to assemble a new world-leading cohort of approximately 15 faculty. The positions include tenure-track Assistant, Associate, and Professor ranks.

A relatively new field, Sociogenomics encompasses theoretical and methodological approaches across the social, behavioral, and genetic sciences including those with an emphasis on computation. It explores the roles of genetics in social and behavior outcomes, as well as how genetics interact with the environment and social forces. Purdue is strongly committed to establishing a pre-eminent center in this emerging area including hiring a substantive cohort of scholars. We are especially interested in fostering collaborative linkages across the core fields of this discipline, here at Purdue and more broadly. This search is open to leading scholars in any area relevant to the advancement of Sociogenomics, and we are especially interested in candidates who draw from and contribute to research in the social science disciplines, biological sciences, the computational and data sciences, statistics, or other related disciplines. We anticipate joint appointments across departments where appropriate, with tenure homes flexible and negotiated at the time of hire.

That is remarkable. Right now, universities everywhere are struggling, thanks to the pressures of the pandemic and political neglect, yet somehow, Purdue has magically come up with the money and the will to create 15 faculty positions in this “relatively new field.” This is not how it works. You start with a small team of qualified people in the area, see how successful they are at grants and papers, and how well the students respond to their courses. Then you build around that solid core and grow the department. Also, you typically start with some well-established discipline that you know has a good track record.

Just flash, boom, creating a substantial department out of whole cloth, hiring new people and assembling them into some kind of framework, is what you do when you’ve got some wealthy sugar daddy, a billionaire or two or some corporation that thinks there are profits to be made. And doing it with some vague discipline that is only a few years old — unthinkable. In the absence of a need, this has to be the product of someone with an agenda, probably an unsavory agenda, pushing buckets of money at a university that will happily accept it.

The thing is, ideas that promote the belief that the very rich have earned their money by virtue of their superior biology are ridiculously popular with the people who have an excess of money to donate.

Feature, or bug?

I wonder what their CEO thinks of this statistic: Antisemitism on Twitter has more than doubled since Elon Musk took over. I’d want to do something about that, if I were in charge, but maybe the billionaire thinks it’s a good thing.

In the days after Elon Musk took over Twitter in October 2022, the social media platform saw a “surge in hateful conduct,” which its then safety chief put down to a “focused, short-term trolling campaign.” New research suggests that when it comes to antisemitism, it was anything but.

Rather, antisemitic tweets have more than doubled over the months since Musk took charge, according to research that I and colleagues at tech firm CASM Technology and the Institute for Strategic Dialogue think tank conducted. Between June and October 26, 2022, the day before Twitter’s acquisition by Musk, there was a weekly average of 6,204 tweets deemed “plausibly antisemitic”—that is, where at least one reasonable interpretation of the tweet falls within the International Holocaust Remembrance Alliance’s definition of the term as “a certain perception of Jews, which may be expressed as hatred towards Jews.”

Personally, I don’t understand how anyone can fear and hate a particular ethnicity, or maybe all ethnicities other than their own. Do these people just sit around seething about the existence of Jewish people, people they probably don’t even know? Do they need a scapegoat for their own problems? Have they considered that maybe it’s their own brain that is screwed up, and that they should get therapy?

Here’s another thing I don’t understand.

Antisemitic tweets directed at Jewish investor and philanthropist George Soros warranted its own category. He was mentioned more than any other person in our data, over 19,000 times, with tweets claiming he was a member of a hidden globalist, Jewish, or “Nazi” world order.

One would think there should be little confusion about whether someone is Jewish or Nazi. Those seem to be mutually antagonistic categories.

Also, I can go days to months without even thinking of George Soros, he has so little influence on me. The only time I am reminded of his existence is when some antisemitic weirdo tells me I’m his puppet.

Stump the right-winger

Who the heck is Bethany Mandel? I had to look her up on Wikipedia to find out: she’s a conservative pundit, one of those weird libertarian goons.

She transferred to Rutgers University in 2005 for its strong Jewish Studies department and Jewish student community, and worked full-time while a full-time student, graduating in 2008 with a degree in history and Jewish studies. During her college years, she adopted conservative views after finding that Medicaid and other government welfare programs she had expected to help her after her mother’s death were inefficient and ineffective, objecting to the idea that as someone who had grown up in poverty, she had any ‘white privilege,’ as well as due to the influence of college friends and the writings of Ayn Rand.

She has recently written a book titled Stolen Youth, about how the left is waging an all-out battle on the American family, particularly the youngest members. If they can make our children miserable, lead them to question every building block of society, and rebuild their entire concept of reality, then the left and their woke indoctrinators will consider that a victory. Right. That kind of popular right wing fanatic.

I don’t have any sympathy for the kind of fame she’s getting right now. She was being interviewed, and was asked to define “woke”. Watch her brain short circuit — it’s quick.


“Woke” is the understanding that we need to totally reimagine and redo society in order to create hierarchies of oppression

She did manage to scrape up a very bad definition: “woke” is not about being aware of systemic bias, it’s about creating hierarchies of oppression, which is kind of the absolute opposite of the idea. No wonder she hates it!

That’s a good way to handle these clowns: just ask them to define what they’re railing against, and either they’re going to give an accurate definition (as Desantis did, “the belief there are systemic injustices in American society and the need to address them”), which made him look like a hateful idiot for opposing it, or they have to invent a fake definition (like Mandel, the need to reimagine society in order to create hierarchies of oppression) and look like an ignorant idiot.

Good work, Briahna Joy Gray. You made that skewering look effortless.

“woke”

The most useful thing about the word “woke” is that it allows me to instantly recognize the lying idiots. All these conservatives complaining about “wokeism”…it’s like they’ve tattooed “LOSER” on their foreheads, and they’re proud of it.

Ron Desantis, of all people, gave the game away when his lawyers had to explicitly define “woke”, and this is what they came up with.

Asked what “woke” means more generally, [Desantis’ General Counsel Ryan] Newman said “it would be the belief there are systemic injustices in American society and the need to address them.”

Newman added that DeSantis doesn’t believe there are systemic injustices in the U.S.

That’s a fine definition, and that Desantis “doesn’t believe there are systemic injustices in the U.S.” confirms my opinion that those who use the word disparagingly are all lying idiots.

I am surprised and reassured to learn that I’m not some weird outlier in this, as well: in one poll, a majority agree that “woke” is not an insult.

Republican presidential hopefuls are vowing to wage a war on “woke,” but a new USA TODAY/Ipsos Poll finds a majority of Americans are inclined to see the word as a positive attribute, not a negative one.

Fifty-six percent of those surveyed say the term means “to be informed, educated on, and aware of social injustices.” That includes not only three-fourths of Democrats but also more than a third of Republicans.

Overall, 39% say instead that the word reflects what has become the GOP political definition, “to be overly politically correct and police others’ words.” That’s the view of 56% of Republicans.

I disagree that it’s a mistake for Republicans to abuse the term, since a majority of them think it’s a synonym for “politically correct.” It’s a rallying cry used to gather all the lying idiots under the banner of whatever yahoo is running for office, and in that sense it’s effective, as long as you don’t mind using language dishonestly and misrepresenting what people actually think.

I find it a handy flag to recognize that someone doesn’t believe systemic injustices exist, and that they sure don’t feel any need to oppose injustice, because they think everything is hunky dory, and we should just maintain the status quo. It certainly has made it fast and easy to spot bad people to block on social media.

But here, I’ve got a video from Cody Johnston that explains the whole absurd, horrible situation at length, almost an hour of length. It’s an entertaining and theatrical and detailed hour, though, so you might enjoy it more than my cursory dismissal of anyone who thinks “woke” is a bad thing.

I’m invited!

The Board of Regents is visiting campus, and I found this invitation slipped under my office door. (Not from the Regents, obviously.)

This is clearly a dig at a certain regent who made some stupid comments. I’d like to go, except…

  1. My attendance would contribute nothing to diversity
  2. Nobody from the Board of Regents will bother to show up
  3. That’s my birthday! Can’t I find a better way to celebrate it?

My counterarguments would be…

  1. But it would show that even old white men support diversity
  2. I care what the students think, not the Board of Regents
  3. No.

I guess that’s my Thursday evening planned out then.

You knew this combo was coming

Scott Adams makes a blatantly racist rant and his comic strip is dropped from a large number of newspapers; guess who rushes to defend him? That privileged child of apartheid, Elon Musk.

Twitter and Tesla chief Elon Musk defended Scott Adams, the under-fire creator of “Dilbert,” in a series of tweets Sunday, blasting media organizations for dropping his comic strip after Adams said that White people should “get the hell away from Black people.”

Replying to tweets about the controversy, Musk said it is actually the media that is “racist against whites & Asians.” He offered no criticism of Adams’s comments, in which the cartoonist called Black people a “hate group” and said, “I don’t want to have anything to do with them.”

That is the least surprising alliance since the Rome-Berlin Axis.

Well, I guess we all have to start reading Dilbert, since Elon says so.

Hmmm, I was right?

I said we should cancel Scott Adams, and gosh, look what happened: people spoke up all across the country, and Scott Adams was canceled.

Newspapers across the United States have pulled Scott Adams’s long-running “Dilbert” comic strip after the cartoonist called Black Americans a “hate group” and said White people should “get the hell away from” them.

I guess it’s easy to be a prophet when you predict the obvious stuff.

One could argue that this means Adams will be whining indignantly about injustice and those damned libs some more, but that’s fine, he has free speech, he can complain all he wants, I simply won’t be hearing about it and can take some satisfaction in the fact that he won’t be making as much money off his bigotry anymore.

Tomorrow is a “Day of Hate”

There’s nothing anyone can do about it, I guess, but anti-semitic, that is, NAZI organizers are telling their followers to carry out acts of harassment against Jewish people on Saturday. The police are just warning you all — you’re on your own, nothing they can do.

Chicago police are urging Jewish and other religious communities to be extra vigilant this weekend when a neo-Nazi group has declared a “day of hate.”

“At this time, there is no actionable intelligence,” the Chicago Police Department said in a statement. “We continue to actively monitor the situation.”

In New York, the police will have “elevated situational awareness”, but otherwise, it’s on you to be careful.

In the warning, the NYPD advised officers to maintain “elevated situational awareness” on Saturday, particularly at locations that “might garner higher interest from these types of actors.”

What good are the police, then? Once the bodies have bled out, then they can step in? I have noticed that the police are pretty darned good at making life miserable for black people, harassing them with frequent traffic stops, hassling them on street corners, threatening them with arrest for trivial actions, even too often outright killing them — I don’t want cops murdering skinheads either, but it seems to be easier to stroll around with a swastika tattoo than the unadorned skin a black person is born with. The police have the tools, they use them when they wish, but apparently, they don’t wish to crack down on white people threatening violence to other citizens.

In addition to the uselessness of cops, do these Nazis have even an ounce of introspection? Declaring a “Day of Hate” really ought to be enough for any normal person to realize that they are the baddies. The very baddest baddies. I guess the fact that they’re wearing swastika arm bands should have been the first clue, but they ignored that and are just going to run all the way to beating up little old Jewish ladies in the street, because they generically hate them.