Want to see some real science? An article in the NY Times summarizes research in the evolution of glucocorticoid receptors. This is really cool stuff, where the investigators do step-by-step changes in the protein structure to determine the likely sequence of evolutionary changes — it really does describe the path of evolutionary history for a set of proteins at the level of amino acids.
Now, if you want to see some junk science, Michael Behe flounders disgracefully to try and dismiss the work. This is a genuine embarrassment: Behe is a biochemist who has done legitimate work in protein structure, and this kind of research ought to be right up his alley, where he could make an informed analysis. Instead, it’s ugly and sad. A sensible creationist would simply admit that sure, here’s one case of the evolution of a receptor that is solidly made, but hey, look, over there — here are all these other proteins that haven’t been analyzed to the same level of detail. It would be pathetic and avoiding the issue, but Behe has a different and worse strategy: he denies the work shows anything at all. Because the researchers intentionally inserted mutations into the gene, they can’t argue that natural processes of mutation could have done the same thing. But of course we do know — point mutations happen all the time.
Behe continues his long slide into tendentious irrelevance and lunatic obsessions. Jason Rosenhouse digs into this step in Behe’s descent into unreason in much more detail.

