Darwin Day approaches

It’s almost Darwin Day!

I just learned that Cornell is going all out: 5 days of events celebrating Darwin’s birthday, on February 9-13. That’s darned good.

The University of Minnesota Twin Cities is doing something slightly smaller in scale on Friday, 10 February, in an afternoon event sponsored by the Campus Atheists and Secular Humanists. I don’t have all the details yet, other than the rather important fact (to me, at least) that I’m one of the speakers. I’m planning to talk on “What Darwin Didn’t Know,” giving a brief overview of some examples of the kind of evidence uncovered in the last 25 years that has greatly strengthened evolutionary theory. I’ll put up a schedule here as I learn more.

We aren’t having a specific Darwin Day event here at UMM…well, other than the traditional cake and ice cream I’m planning to have with the family on that Sunday. However, the Cafe Scientifique Morris for February is going to be me, talking about evolution and creationism. That’s also imprecisely scheduled at this point—we’re going to try out a new venue, I hope, and one of the things I have to do this week is run around and work that out.

I know, I know—Darwin Day is over a week away, and you just can’t wait. If you’re in the Twin Cities, here’s something to whet your whistle: a talk tonight on creationism.

7:00 pm – James Curtsinger – Ten things to know about creationism
James Curtsinger will give a presentation on “Ten Things to Know about Creationism”.

From the presentation: Creationists fall into young-earth and old-earth camps. The former include biblical literalists who believe that the geologic column was formed by a Noachian Flood. Their “scientific creationism” suffered major setbacks in the 1980’s. “Intelligent design”, conceived as a movement in the 1990’s, is smarter, better educated, old-earth creationism. I.D. has popular support, but is soundly rejected by professionals, and was embarrassed in the recent Dover trial. The important battleground for these issues is the public high school science classroom. Surveys show that 20% of MN public high school science teachers teach creationism. Evangelical atheists worsen the general problem. Universities house technical and scientific expertise, but do not generally cultivate the kind of outreach needed to address this issue.
Coffman Student Union Room 323

I’d love to attend myself, but I’m feeling that exhausted sensation that comes from the first few frantic weeks of classes, and I don’t think I can push another long drive to Minneapolis on my workload right now. If any of my readers go—send me a report! It sounds fun!

President panders to anti-manimal lobby! Dr Moreau flees country in rage!

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I didn’t listen to the State of the Union Address last night, preferring to maintain my equanimity by attending a talk on quantum physics, but I knew I could trust my readers to email me with choice weird science bits. I’m getting a lot of “WTF?” email about this statement from Bush:

Tonight I ask you to pass legislation to prohibit the most egregious abuses of medical research, human cloning in all its forms, creating or implanting embryos for experiments, creating human-animal hybrids, and buying, selling or patenting human embryos.

It’s pure political calculus. He throws away the mad scientist and pig-man vote, and wins the religious ignoramus vote…and we know which one has the majority here.

But guess what? Creating chimeras is legitimate and useful scientific research; it’s really happening. Of course, it isn’t with the intent of creating monstrous half-animal/half-human slaves or something evil like that, and scientists are well aware (or should be well aware) of the ethical concerns, and it’s the topic of ongoing debate. Let’s consider one recent example of such an experiment.

Down syndrome is a very common genetic disorder caused by the presence of an extra chromosome 21. That kind of genetic insult causes a constellation of problems: mild to moderate mental retardation, heart defects, and weakened immune systems, and various superficial abnormalities. It’s also a viable defect, and produces walking, talking, interacting human beings who are loved by their friends and families, who would really like to be able to do something about those lifespan-reducing health problems. We would love to have an animal model of Down syndrome, so that, for example, we could figure out exactly what gene overdose is causing the immune system problems or the heart defects, and develop better treatments for them.

So what scientists have been doing is inserting human genes into mice, to produce similar genetic overdoses in their development. As I reported before, there have been partial insertions, but now a team of researchers has inserted a complete human chromosome 21 into mouse embryonic stem cells, and from those generated a line of aneuploid mice that have many of the symptoms of Down syndrome, including the heart defects. They also have problems in spatial learning and memory that have been traced back to defects in long-term potentiation in the central nervous system.

These mice are a tool to help us understand a debilitating human problem.

George W. Bush would like to make them illegal.

He’s trusting that everyone will think he is banning monstrous crimes against nature, but what he’s really doing is targeting the weak and the ill, blocking useful avenues of research that are specifically designed to help us understand human afflictions. His message isn’t “We aren’t going to let the mad scientists make monsters!”, it’s “We aren’t going to let the doctors help those ‘retards.'”

Once again, the ignorance and the bigotry of the religious right wins out over reason and humanitarianism. I think I know who the real pig-men are.

O’Doherty A, Ruf S, Mulligan C, Hildreth V, Errington ML, Cooke S, Sesay A, Modino S, Vanes L, Hernandez D, Linehan JM, Sharpe PT, Brandner S, Bliss TV, Henderson DJ, Nizetic D, Tybulewicz VL, Fisher EM. (2005) An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science 309(5743):2033-7.

I know this irritates my critics…

…but my university actually supports me. There’s a profile of yours truly that’s part of a random rotating collection of links on UMM’s main page (if you don’t see it there, reload the page; it’ll appear eventually.)

I am aware that I am slightly harsher and more radical than many of my colleagues on some issues (others have their own domains of expertise and radicalism), but one of the great things about UMM is that even if they don’t explicitly endorse all of my opinions—and that acknowledgment on the main page is not an admission that this university is a hotbed of militant atheist evilutionists—they are appreciative of the diversity of ideas that make up a great university.

More Koufax nominations!

I’ve got a couple of posts that have been nominated for The 2005 Koufax Awards: Best Post, so I’ve quickly brought them on board here at the new site. Voting isn’t yet open, but here they are:

  • Idiot America. This one is something of a howl of anguish, and it’s really more a lot of quotes from Charles Pierce’s article of the same name in Esquire. If this gets the nomination, credit should go more to Pierce than to me—and that’s OK.
  • Planet of the Hats. This article is probably the best representation for how I actually feel about religion. It’s all metaphor, but if you don’t get it, I won’t be surprised…it means you’re really, really, ummm, devout.
  • The proper reverence due those who have gone before. I have to say, if one of these three gets the nomination, this is the one I’d personally favor. But hey, you’re all supposed to vote for your favorite, and there are about 220 other great choices there, too. Anyway, if you want to understand why I despise creationists of all stripes, this article might help you understand why.

The proper reverence due those who have gone before

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Some people might think I’m a rather morbid fellow. Years ago, when I was an undergraduate lackey at the University of Washington and working at the med school, there, I made a wonderful discovery one lunch hour: a bone room. Tucked away in an odd corner of the building was a room full of shelves stacked with cardboard boxes, each one containing the bones of some individual who’d left their remains to science. They’d been thoroughly cleaned and disarticulated, and many had parts sawed apart so you could peer into the sinuses or the hollow spaces for marrow or poke around in the caverns of the cranium. It became my favorite quiet, private place. I could putter about reassembling someone, or just contemplate some scrap of bone for a Yorick moment.

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SOTU prognostications

Well, Kevin Drum’s prediction about the State of the Union address is a bit vague and general:

Bush’s theme may well be that he’s right and his critics are wrong; and his vision may well be of a year of partisan trench warfare with congressional Democrats.

But Chris Mooney gets specific:

A while back I blogged about an idea floated by Morton Kondracke: That George W. Bush should try to become the “science” president by emphasizing, in his State of the Union speech, themes of global scientific competitiveness and the need to ensure that the good old USA is leading the pack. Well, it now seems official: According to the Boston Globe, in his speech tonight Bush plans to highlight Norman Augustine, a former Lockheed Martin CEO who “last year led a congressionally mandated National Academies team that issued a report warning that America is ‘on a losing path’ in the global marketplace.” Why are we falling behind? If you believe the NAS, it’s because of inadequate scientific and mathematical training for our high school students, not enough funding of basic scientific research, etc etc.

I won’t be watching it—I have a Cafe Scientifique to attend tonight, and if I want to watch an evil buffoon on TV, I have some Blackadder DVDs—but if Bush tries to claim he’s going to be the Science President, I’m going to laugh and remind everyone that Bush endorses Intelligent Design creationism. I’m also going to remember that he called himself the Education President, and what we got from that was an unfunded demand that everyone teach to the test.