The lesson of apples


I grew up in Washington state, and many of my relatives worked the apple orchards in season — they were good, hardworking fruit pickers. But I hadn’t even thought about where apples came from. I was pretty sure it wouldn’t have been the Yakima valley, and of course I knew of the legend of Johnny Appleseed, but wouldn’t have been able to even guess what their origin was.

It turns out they’re from Kazakhstan.

What I thought was most interesting in the video is that it mentions Nikolai Vavilov, and his famous hypothesis — so famous that we take it for granted in any discussion of human origins.

The origin of any cultivated plant can be found where its wild relatives grow with the greatest diversity.

Awesome! I’m going to have expand my discussion of extreme heterozygosity and centers of origin in my Spring semester genetics class (but not now, I have to focus on cell bio for next week). I read this most excellent review, Human-driven evolution of cultivated plants and the origin of early civilizations: The concept of Neolithic revolution in the works of Nikolai Vavilov and found it enlightening.

The concept of centers of origin of cultivated plants (crop biodiversity hotspots) developed by Nikolai Vavilov (1887–1943) is essential for understanding the origin and evolution of human civilization. Vavilov formulated the principles of the Neolithic agricultural revolution and substantiated the basic patterns for the emergence of agricultural civilizations. He established that the center of speciation of the plants that have a potential for cultivation determines the origin of primary civilization. Humans actively performed the selection of plants with valuable properties, which led to the formation of new cultivated species and varieties, while the starting point for such unconsciously human-directed evolution was the presence of potentially useful traits due to the increased genetic diversity in the center of origin. The spreading of agriculturally important cultivars from the center of their origin led to the propagation of beneficial farming technologies over large areas. The establishment of human civilization resulted from the dynamic quasi-symbiotic relationship between humans and domesticated plants and animals, which human-driven evolution became an essential factor for the transformation and dynamics of human societies.

Here’s all the human history you need. (I exaggerate slightly.)

Fig. 5 summarizes the proposed views on the development of agricultural civilizations and phytospreading during the Holocene. The phytospreading process became to a major extent human-driven in the Holocene, which resulted in intensive biomass formation related to the production of crops. Centers of origin of cultivated plants determined the rise of early civilizations, which in turn facilitated the spreading of wild, cultivated, and weed species to higher latitudes. The process of phytospreading in the Holocene was described by Vavilov for the origin and distribution of cultivated plants. He identified the centers of origin of cultivated plants as the hotspots of genetic diversity for the plants potentially having agricultural importance. In these spots, the series of parallel variability (described as Vavilov’s law of homologous series) were very intense.

Fig. 5. Schematic illustration of the development of agricultural practices, spreading of cultivated plants, and social evolution of human civilization.

The law of homologous series is a very evo-devo concept. It’s the idea that similar variations can be found in members of the same genus, the same family, that is, that there seems to be something in the ancestral form that recurs spontaneously in later descendant forms, that the feature is an intrinsic property that can pop up in multiple branches of a lineage. These are brilliant observations rooted in Vavilov’s extensive study of native populations. Yes, he visited Kazakhstan and studied the apples there.

It’s especially impressive that he was doing this work that merged the disciplines of evolutionary biology and genetics in the 1920s.

You may have heard Vavilov’s name in another context: he was hated by the anti-science ideologue Trofim Lysenko, who eventually had him arrested and condemned to death in 1940. Vavilov died in prison in 1943, all because he recognized the scientific validity of Mendelian genetics, and opposed the nonsensical delusions and wishful thinking of Lysenko (delusions that led to the death of millions by famine). I can’t help but notice the similarities in the conflict between American science and the lies of MAHA and our modern Lysenko, RFK jr.

Vavilov’s mugshot

Thank goodness no scientists are being harassed in show trials and threatened with prison here! How many great scientists are going to wither on the vine thanks to the current radical politicization of science in this country?

Comments

  1. raven says

    Thank goodness no scientists are being harassed in show trials and threatened with prison here!

    This must be sarcasm.

    Anthony Fauci was one of the heroes of the Covid-19 virus pandemic.
    We just had a show trial for him in congress, chaired by a GOP MD, Rand Paul.
    He has been referred to the misnamed DofJ for further torture.
    Fauci’s crime was being right, hard working, and effective in fighting the pandemic.

    The only reason the terrorists and quacks of the GOP aren’t referring more scientists and MDs to the fake DofJ is that they don’t know any more scientists by name or what they did.
    These people are all pretty dumb.

    How many great scientists are going to wither on the vine thanks to the current radical politicization of science in this country?

    They may not all be great scientists, whatever that means, but at least tens of thousands of US scientists will lose their jobs, do nothing, and change their careers because of the huge cuts in funding.

    The other victim will be the USA and the American people.
    Science is the driver of our civilization and the basis of the US economy.
    The leading countries in the world all have high spending on Research and Development.

  2. robro says

    For more on the “legend” of Johnny Appleseed, aka John Chapman (1774 — 1845), see the first part of Michael Pollan’s The Botany of Desire: A Plant’s-Eye View of the World (2001). It’s an enjoyable read, although I can’t swear to the historical accuracy. Based on Pollan’s description, you might say Chapman was a model for an American entrepreneur…as American as apple pie.

    Per Pollan, the reason for growing apples was to make cider, specifically hard cider because beer was rare in those days. Chapman collected seeds from the cider houses in Pennsylvania then canoed down the Ohio River then up the side stream to find places to plant the sees. He would come back later to collect saplings and sell them to the settlers.

    In the vein of Vavilov’s ideas, I have read that wheat originated from a wild species of Einkorn that came from the Karaca Dağ mountain in eastern Turkey, and Emmer wheat from the Fertile Crescent.

  3. raven says

    Here is the quack, RFK jr.’s latest delusion.

    RFK Jr: “The polio vaccine “killed many, many more people” than polio ever did.”

    This is false.
    This doesn’t even rise to the level of a lie.
    RFK jr. is a delusional loon.

    I know this because I lived through the last polio pandemic and saw the damage up close.
    It was just luck that I didn’t get it myself.

    In the third grade, one day I went to school.
    The playground was in chaos. One of our classmates had died and it had never occurred to us that young kids could die. That only happened to old people, pets, and on TV.
    The word went around. Polio.
    We all knew what polio was.
    A lot of adults, including one of our teachers, limped in various idiosyncratic ways.
    And we all knew about the iron lungs. Thousands of people were trapped in iron lungs for life from polio. It was something we all dreaded.

    I’ve since seen an older adult die from post-polio syndrome.
    Mitch McConnell, the notorious anti-human senator from Kentucky has multiple health problems, one of which is left over from the polio he got as a child.

    And, there was a happy ending.
    I remember when the polio vaccine was developed and everyone rushed to get it.
    I got 4 doses myself .

  4. robro says

    raven @ #1 — Yes, I’m confident that’s sarcasm.

    raven @ #2 — It’s difficult to imagine how a person even at Junior’s age…a mere child compared to some (me)…could have the idea in his head that the vaccine killed more than polio. The message was very strong when I was a child in the early 50s that polio was a scary and devastating disease. If it didn’t kill you, it could leave you crippled or maimed for life. I was in 1st grade and my classroom was just across a walkway from an annex classroom where they gave the shots. Lots of wailing. But we did it and more of us are here to testify to it.

  5. Reginald Selkirk says

    How the Silk Road Created the Modern Apple

    A genetic study shows how wild Kazakhstan apples dispersed by traders combined with other wild species to create today’s popular fruit (2017)

    Almost all of the new apple varieties being introduced are bred from Honeycrisp, which was bred at the University of Minnesota. Which should give Minnesota special status in apple civilization.

  6. Reginald Selkirk says

    @2 robro

    In the vein of Vavilov’s ideas, I have read that wheat originated from a wild species of Einkorn that came from the Karaca Dağ mountain in eastern Turkey, and Emmer wheat from the Fertile Crescent.

    Bread wheat is the result of a chance hybridization, and to understand it you need to introduce the concept of polyploidy.
    Evolution and origin of bread wheat

    Abstract

    Bread wheat (Triticum aestivum, genome BBAADD) is a young hexaploid species formed only 8,500–9,000 years ago through hybridization between a domesticated free-threshing tetraploid progenitor, genome BBAA, and Aegilops tauschii, the diploid donor of the D subgenome. Very soon after its formation, it spread globally from its cradle in the fertile crescent into new habitats and climates, to become a staple food of humanity. This extraordinary global expansion was probably enabled by allopolyploidy that accelerated genetic novelty through the acquisition of new traits, new intergenomic interactions, and buffering of mutations, and by the attractiveness of bread wheat’s large, tasty, and nutritious grain with high baking quality. New genome sequences suggest that the elusive donor of the B subgenome is a distinct (unknown or extinct) species rather than a mosaic genome. We discuss the origin of the diploid and tetraploid progenitors of bread wheat and the conflicting genetic and archaeological evidence on where it was formed and which species was its free-threshing tetraploid progenitor. Wheat experienced many environmental changes throughout its evolution, therefore, while it might adapt to current climatic changes, efforts are needed to better use and conserve the vast gene pool of wheat biodiversity on which our food security depends.

  7. Pierce R. Butler says

    Humans actively performed the selection of plants with valuable properties, which led to the formation of new cultivated species and varieties…

    Which makes it sound like a deliberate program of research and development.

    More likely, the plants most valued (for taste, crop yield, etc) had their seeds deposited most often in the trash heaps and pooping places, and were gleaned more in the following harvest seasons – a Darwinian virtuous-cycle process necessary to make deliberate agriculture possible as (locally) expanding populations forced its adoption (farming is much more work than gathering). Tangentially, I suspect most of these trends were observed and applied by women.

  8. Pierce R. Butler says

    … he was hated by the anti-science ideologue Trofim Lysenko, who eventually had him arrested and condemned to death in 1940.

    I haven’t heard of any meetings between RFKJr & Putin, but if they happen(ed), surely the latter would inform the former of how the glorious Russian past could guide the future they both want for the USA.

  9. Daryl Lafferty says

    I have heard that there is more human genetic diversity in Africa alone than in all the rest of the world, which supports that we originated in Africa. Not that there is any question about that.

  10. Hemidactylus says

    raven @3
    I’m guessing RFK Jr is fear-mongering about SV40, which hasn’t seemed to have become an actual issue and is irrelevant to today’s vaccines:
    https://pauloffit.substack.com/p/robert-f-kennedy-jr-should-stop-talking

    Someone likewise could take a snapshot like this out of context and do even more fear-mongering:
    https://www.npr.org/sections/goatsandsoda/2017/06/28/534403083/mutant-strains-of-polio-vaccine-now-cause-more-paralysis-than-wild-polio

  11. seachange says

    There used to be lots of kinds of apples in and around Silicon Valley. Alas a lot of them got paved over. Humans ruin everything.

  12. bcw bcw says

    Reading the review as a non-expert, I’m curious about the “originates as weeds in the mountain valleys, is then bred into agricultural plant as it moves to the river valleys.” Is the idea that the mountain valleys are good sources of isolated populations of plants so that different mountain valleys will differ greatly in plant characteristics and have a better chance of making something desirable to humans to start breeding with? I gather this result was observational for Vavilov but is it correct that the genetic variability of isolated populations is the cause?

  13. bcw bcw says

    @11 IBM in San Jose had a small apple orchard along Cottle Rd on the plant campus because it allowed some sort of farm tax deduction.

  14. StevoR says

    @9. Daryl Lafferty : “I have heard that there is more human genetic diversity in Africa alone than in all the rest of the world, which supports that we originated in Africa. Not that there is any question about that.”

    Correct. Via Phys dot org (may annoyingly require you to watch ashort ad before seeing.) have added the bold emphasis :

    Well-resourced environments favor European-based research generating hundreds of thousands of whole human genomes with associated health data. Yet modern humans, our species, evolved on the African continent. African populations therefore contain the deepest branches of human genetic history and the greatest genetic diversity on the planet. Yet the continent remains strikingly underrepresented in global genomic databases.

    The African continent is populated by people from over 2,000 ethnolinguistic groups, yet genetic data exist for fewer than a hundred groups. This is akin to having a GPS map of a city with only 5% of the streets marked and the rest left blank.

    This bias has profoundly shaped modern medicine, from disease prediction tools to ancestry testing. And it’s why researchers increasingly recognize that studying African genomes has the potential to reveal insights and health-related biological pathways never observed before.

    Source : https://phys.org/news/2026-05-africa-world-greatest-genetic-diversity.html

    Plus :

    Africa’s deep reservoir of genetic information testifies to its role as the birthplace of modern humans. The diversity within African populations surpasses that of all other continents combined, offering a resource for understanding how humans have evolved and adapted.

    Source : https://biologyinsights.com/african-genetics-the-foundation-of-all-human-diversity/

    Again emphasis added by me.

    In addition to :

    In 2009, a geneticist named Sarah Tishkoff and an international team spent a decade trekking across Africa — into remote valleys, onto mountaintops, sometimes powering their equipment with car batteries — to collect DNA samples from more than 120 populations. The study, published in the journal Science, was the most comprehensive survey of African genetic diversity ever conducted.

    What they found reshaped population genetics: Africa has more human genetic diversity than the rest of the world combined.

    The team identified 14 ancestral genetic clusters across all of humanity. Nine of them are in Africa. The remaining five account for every person in Europe, Asia, Oceania, and the Americas. “You’re seeing more diversity in one continent than across the globe,” Tishkoff said.

    Source : https://www.theglobalwow.com/africa-genetic-diversity/

    That also notes furtehr down : “The most striking implication: two San people from the same village can be more genetically different from each other than a European person is from an East Asian person.”

    Which is really rather absolutley staggering.

    But willfully ignorant, toxic, racist scumbags will still pretend “African”genes are one thing and all inferrior to everyone elses becuase, well see a=djectives in accurate description of them starting with second word of this sentence.

  15. beholder says

    @14 StevoR

    Yet the continent remains strikingly underrepresented in global genomic databases.

    This bias has profoundly shaped modern medicine, from disease prediction tools to ancestry testing.

    A solid win for Africans. Don’t let the police state put your DNA in their mass surveillance databases. They will use it against you.

  16. John Morales says

    beholder, more of your false insinuations and slanted propaganda.

    Don’t let the police state put your DNA in their mass surveillance databases. They will use it against you.

    How so?

    Heh.
    The phrase “police state” is doing all the ‘argumentative’ work; your ‘argument’ is not about DNA; it is about generic suspicion of state power.

    Seriously, jokes aside, you might as well have written
    “They will use your fingerprints against you.” or
    “They will use your face against you.” or
    “They will use your phone metadata against you.”

    No less implicature of possible harm thereby.

  17. StevoR says

    @15. Trump its troll beholder : No a solid loss as the linked article says.

    Because Science gives us the knowledge that can then be used to help eg with genetic diseases and issues and forewarn people of such, etc…

    Obvs!

    Also fucking paranoid much?

    Oh and, of course, the USoA was NOT a police state with eg ICE thugs recruited from the far reichwing until they got the POTUS you helped install and worked for.

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