That is good news: it’s a crap show, and the few times I saw it, it was agonizingly unfunny and relied on the audiences lack of understanding of what science nerds are actually like (hint: they’re mostly human, with just a few odd obsessions).
It’s been on twelve years, though? OK, somebody enjoyed it somewhere. I won’t be celebrating its demise, then, because I got all the celebrations out of my system when I saw it 11½ years ago and decided I wouldn’t be watching that garbage ever again. Therefore, the end of their run won’t affect my life in the slightest.