Scientists behaving deviously

Cas9

There are some scientific technologies that rapidly become ubiquitious and indispensible, and they become the engine that drives tremendous amounts of research, win Nobel prizes, and are eventually taken for granted. Polymerase chain reaction (PCR) is one example: PCR is routine in molecular biology now, but I remember when PCR machines were magical objects of reverence, and you were cutting edge when you used one. No more; I actually tell my senior students presenting their final thesis presentation that they don’t have to explain what PCR is anymore, everyone knows what it is and how it works and what it is used for.

The new technology of today that is going to be showered with awards and money and accolades and become totally ubiquitous is CRISPR/Cas. This technique exploits the molecular biology of a prokaryotic adaptive immune system to target gene sequences in living cells and swap in a different sequence — it’s a mechanism for going into a cell and editing its genome selectively. This is huge. It has gigantic implications — people are already fretting over the ethical use of a way to modify people’s genes, even before it has been applied in any practical way. I’m not exaggerating when I say that this is going to be the universal tool for experimental molecular biology for the next several decades, possibly indefinitely.

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I argued with a cartoon this morning

This one:

Isn’t the cartoon a simple answer to a serious problem? Does that make it wrong?

I also thought about the revolutionary ideas in science, like evolution. Darwin’s answer is not complex — it’s fundamentally very simple — but it has deep implications and complex consequences, and yes, it’s a long and winding road if you try to follow all the details that flow from it. But it’s not the complexity that makes people reject it. If complexity were an objection, there would be no Catholics or Muslims in the world.

It’s the mismatch between simple and wrong perceptions and simple but right reality.

Evolution says that biological change is a property of populations — that every individual is a trial run of an experimental combination of traits, and that at the end of the trial, you are done and discarded, and the only thing that matters is what aggregate collection of traits end up in the next generation. The individual is not the focus, the population is.

And that’s hard for many people to accept, because their entire perception is centered on self and the individual. That’s why they invent stories of life after death and eternal life, because what’s the point if you just live for a brief time, and then die? The point only emerges when you step away from it and see the world from a different perspective, that of the population.

So I have to reject the premise of the cartoon. People are willing to avidly embrace difficulty and complexity if it conforms to their personal biases, if it affirms what they want to be true.

What a fun family!

Today, Sarah Palin endorsed Donald Trump for president (are you at all surprised?). Last night, her son Track was arrested for domestic violence, and for waving a gun around while drunk.

It is all of a piece, a perfect convergence of all-American boorish stupidity. Sarah Palin is America, the America we all wish would stay home and off the television and out of politics.


Oh, my. Have you listened to Palin’s endorsement?

You guys are sounding angry is we’re hearing from the establishment. They stomp on our neck and tell us to chill. Just relax. Well, look, we are mad and we’ve been had. They need to get use to it. This election is more than just your basic ABCs: Anybody but Clinton. It’s more than that this go around. When we’re talking about a nation without borders, and bankruptcies and our federal government, debt our children and grandchildren will never be able to pay off.

When we’re talking about the power that comes from strength, power through strength, well then we’re talking about our very existence. No, we’re not going to chill. It’s time to drill, baby, drill down and hold these folks accountable and we need to stop the self-sabotage and elect a candidate that represents that and America first, finally. Pro-Constitution. Common-sense solutions he brings to the table. Yes, the status quo has got to go. With their failed agenda, it can’t be salvaged, it must be savaged and Donald Trump is the one to do that. Are you ready for new and are you ready for the leader who will let you make America great again? It’s going to take a whole team.

That’s just…I don’t what that is. Stream of consciousness from a brain stuffed with sound bites and magic words, with no conceptual focus to hold them together?

What is going on with the Sioux Falls Free Thinkers?

psychic

I haven’t gone to any of their meetings, but their web site weirds me out. There’s the name: that space makes a difference. Freethought is “a philosophical viewpoint which holds that positions regarding truth should be formed on the basis of logic, reason, and empiricism, rather than authority, tradition, revelation, or other dogma”, and as I’ve said repeatedly, it is not a pointless label for thinking whatever you want (everyone gets to do that, whether you’re a hidebound Catholic or Islamist, or an atheist scientist). So I’m a little skeptical when someone confuses freethought with freedom to think any damn thing.

Then there’s the motto on every one of their web pages: Persistence and determination alone are omnipotent!. Whoa, what? A Calvin Coolidge quote that reeks of Norman Vincent Peale and the Power of Positive Thinking? Look again at that freethought definition — does it mention that truth is determined by thinking really hard and stubbornly about it, or does it say something about “logic, reason, and empiricism”?

And this page: Do People Have Psychic Abilities? Open-Minded Free Thinking at its Finest. It completely misrepresents the status of the science.

Let’s get real. There is no supernatural anything. Nothing is outside of reality. There is no single God, and no Gods, no Ghosts, no Goblins and no Ghouls. They are all fabrications of the human mind in an effort to make sense of what we experience but don’t understand. Our minds create an imagined reality or experience and we accept our imagining as something real. We seek a reason for existence and we just can’t seem to accept that IT JUST IS.

Nonetheless there is strong evidence for anomalous psychic experiences such as extrasensory perception. That doesn’t mean these experiences are outside of reality, that they are somehow supernatural. It just means we don’t understand these experiences and cannot explain them YET. That’s why we use science to study them. First to explicitly identify what it is that people are experiencing, and second to perform further experiments to understand how these experiences physically work.

No, there is no strong evidence for ESP. None at all. It’s been pursued for years by dogged people who think persistence and determination alone are omnipotent, and that if they just keep chasing marginal statistical anomalies with sufficiently sloppy experimental procedures, they will be able to prove that it exists. But the author of this piece has their own interpretation: the scientific establishment has been conspiring against paranormal phenomena.

Unfortunately many skeptical scientists see the study of extrasensory perception as a threat to science. They have already decided these experiences cannot be real. To protect science from the “charlatan” scientists performing these experiments they created a committee to set up rules and tests that the parapsychology research results must pass before they can be accepted as valid science. So the parapsychologists went back, designed tests that met the very strict rules required, and performed the tests again. Many of the tests still came out positive for extrasensory perception. OOPS.

So the skeptical scientists went back to the their drawing board and made the tests virtually impossible to pass for just about any research. One of the skeptical scientists actually quit the committee having realized this was not about making objective tests for parapsychology research to pass. It was about making tests that did not allow parapsychology research to pass PERIOD.

Demanding greater rigor in the face of anomalous results is exactly what scientists are supposed to do; if the phenomena can not survive tests that exclude error and prosaic explanations, than the phenomenon is not what the psychic proponents think it is. This exactly what happened when some physicists found that neutrinos traveled faster than light: a surprising claim like that requires that other, alternative explanations be excluded, and careful repetition and analysis found experimental error that explained the result.

I suppose you could argue that “It was about making tests that did not allow physicists with faster-than-light research to pass PERIOD”. But this is how I see it:

So the chorus has sung and the final curtain has fallen on the faster-than-light neutrino saga. “The story captured the public imagination, and has given people the opportunity to see the scientific method in action—an unexpected result was put up for scrutiny, thoroughly investigated and resolved in part thanks to collaboration between normally competing experiments,” Bertolucci says in a CERN press release. “That’s how science moves forward.” Fair enough. But can we move on now?

The final curtain has also fallen on the psychic powers myth. Can we move on?

#DontCryWolfe

dontcrywolfe

Please don’t. I’ve had to rant at a few people lately who credulously post these superficially cool memes that dissolve into absolutely unworkable nonsense when you think critically about them for even a moment, and they’re all coming from this persistent self-promoter named David Avocado Wolfe. Worst of all, I’m seeing these coming from atheist and skeptic groups, people I’d expect to put a little more thought into the evaluation of claims.

This guy is a cancer quack, and is marketing New Agey supplements that are supposed to do magical things for your body. For instance, he’s selling Himalayan Crystal Salt, which he claims contains 84 natural, essential elements (note that he’s careful not to call them “chemicals”, which are all bad). In addition to sodium and chloride, like the cheap stuff you buy at the grocery store, it also contains trace elements (also like any food grade product you buy at the store), which includes arsenic and plutonium.

Wolfe is a no-talent, incompetent, dishonest fraud: the one skill he has to an extreme degree is in marketing, and the only thing he markets is himself. If you push something at me from David Wolfe, I will cut you off completely.

Libertarians never learn

Once upon a time, a group of them decided to act on their principles and establish a Libertarian paradise in a foreign country: Galt’s Gulch Chile, they called it. What happened next?

Galt’s Gulch Chile is the name of a proposed residential community to be built near Curacaví Chile, approximately one hour west of Santiago and one hour east of the Pacific Ocean. The original principals were John Cobin, Germán Eyzaguirre, Jeff Berwick (The Dollar Vigilante) and KENNETH DALE JOHNSON. Through a series of broken promises, broken contracts and dishonest maneuvers, johnson circleJohnson was able to cut his partners and investors out of the real estate development project and claim 100% ownership and control.

He proceeded to develop, not a community as advertised, but an affinity scam aimed at Western libertarians. Johnson employed deceptive selling practices, violations of US and Chilean law, money laundering, and multiple jurisdictions to defraud his investors of US $10.45 million ($10.05 million with GGC and $400,000 with tangential scams).

Johnson sounds like the ideal Libertarian man, a true Randian hero, living up to the principles of selfishness to the ultimate degree. What’s the complaint? This is exactly what ought to happen if you design a community around the principles of Ayn Rand — perhaps the problem is that Rand didn’t recognize the value of community, and community is rather antithetical to her magical hyper-competent individualists.

The subtitle at that site is restoring the vision. I don’t think they get it.

Not a chance. We’re dedicated to turning Fraud’s Gulch Chile into Galt’s Gulch Chile. That’s what this website is all about.

“Galt’s Gulch” was an absurd idea in the book — maybe they ought to realize that Libertarian ideology is incompatible with civilization. Another pro-Libertarian site is similarly oblivious.

Ayn Rand could never have imagined just how a development based on her fictional novel could have become an even more sordid and unbelievable tale than the book itself… so far it has.

True. Ayn Rand couldn’t. The rest of us, though, could see the nightmare with clarity.

I really picked the wrong line of work, part MCMXII

If I wanted to be rich, I wouldn’t be a college professor. There are many professions that pay so much better.

Like right-wing moocher off of religious charities. LaVoy Finicum, one of the mouthy militia that’s taken over Malheur Preserve, is sad because while he’s gallivanting off to pointless, egotistical crusades in remote places, they have taken his foster children away.

“They” being the organizations that pay him to take care of these kids. On top of neglecting his parental responsibilities, his complaint reveals something of his character. Rather than desperately begging to have his loved ones returned to him, which is how I’d have reacted if Child Protective Services had swept my children away, he’s moaning about the loss of income.

Finicum said he is licensed and has a care contract with Catholic Charities Community Services in Arizona. While his license has not been revoked, Finicum said he would no longer receive referrals to care for foster children.

That represents an enormous loss of income for the Finicums. According to a 2010 tax filing, Catholic Charities paid the family $115,343 to foster children in 2009. That year, foster parents were compensated between $22.31 and $37.49 per child, per day, meaning if the Finicums were paid at the maximum rate, they cared for, on average, eight children per day in 2009.

“That was my main source of income,” Finicum said. “My ranch, well, the cows just cover the costs of the ranch. If this means rice and beans for the next few years, so be it. We’re going to stay the course.”

My first thought: wow, he’s bringing in $100K for taking care of kids (a job he seems to be shirking)? My parents had six kids and were living on $10K a year that my dad had to work two jobs to earn. Clearly, the lesson is that while my father was earning a pittance for hard manual labor, my mother should have been getting paid ten times as much for her hard work raising kids.

My second thought: oh, so this ranching nonsense is really just a hobby for people who have worked the angles and are getting paid beaucoup bucks from charitable institutions? Just like the Bundy family is all anti-government while living on government subsidies? Color me unsurprised.

My third thought, after it all sunk in: those poor kids. They were nothing but a paycheck to their foster parents. It is simply cold, callous venality to say “so be it” when children are taken away, and to regard the great cost of that loss being to have to live on rice and beans. It’s positively Dickensian. May they never have another child brought to their home, and may they die lonely and alone at some distant time.

I may make a lot less money than that exploiter, Finicum, but at least I can say I love my kids, and I came from a happy family, and I’m not a paranoid conspiracy theorist loon, so maybe I actually did pick the right line of work.