OK, gang, help me out here. I’m swamped today — my morning is destroyed because I have to go in to the clinic for my annual thorough extensive physical check-up, and I get out just in time for my afternoon class, and then I’m free, sort of. Except that I have to compose a 10 question online quiz on chromosome variations.
So give me some good questions on deletions, duplications, inversions, and translocations. Preferably questions that can be easily machine-scored, but I do throw in an essay question or two.
Get to work. I’ll expect them in the comments section here when I get back at 1:30.
Don’t disappoint me.



Maybe too easy:
What explains the difference in the number of chromosomes between H. Sapiens (46) and other simians (e.g. the 48 of Pan troglodytes)? What evidence supports supports this?
Assuming that Cheez-Whiz is derived from “Cheez”, and Cheez is a mutant strain of actual Cheese, how would the original Cheese’s chromosomes differ from the final product?
Support your conclusion with peer-reviewed citations (or lots of exclamation points).
How does trisomy 21 happen in 95% of cases ?
a) Meiotic Nondisjunction (95% of cases): The egg or sperm cell retains both copies of chromosome 21 instead of one, resulting in a zygote with three copies.
this one seems a bit basic. I probably could have done better but I’m tired.
What is the sound of one endonuclease clipping?