Epigenetics

Blogging on Peer-Reviewed Research

Epigenetics is the study of heritable traits that are not dependent on the primary sequence of DNA. That’s a short, simple definition, and it’s also largely unsatisfactory. For one, the inclusion of the word “heritable” excludes some significant players — the differentiation of neurons requires major epigenetic shaping, but these cells have undergone a terminal division and will never divide again — but at the same time, the heritability of traits that aren’t defined by the primary sequence is probably the first thing that comes to mind in any discussion of epigenetics. Another problem is the vague, open-endedness of the definition: it basically includes everything. Gene regulation, physiological adaptation, disease responses…they all fall into the catch-all of epigenetics.

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Not again…

Bill Donohue has once again issued a press release, urging all of his followers to harass my in-box. Once again, my email is rendered useless by a flood of idiots sending me bizarre tirades and links to Catholic fables and threats. There is a new change in tone: now lots of them are gloating that they’ve written to CAIR, and the Muslims are now going to come and blow up my house, ha ha! Thanks, Donohue, for reinforcing prejudice about Muslims.

I may have to simply dump all email sent to my more public addresses and create new accounts that I’ll only make known to a sensible few. It’s that bad.

Time for a brief break

It’s been a high-stress week — not because of anything on the blog, I assure you, since that’s all been chaos over trivialities — but because all my recent travel has put me far behind on a lot of work, with missed deadlines and heaps of writing that had to be done right now. A significant chunk of all that has been polished off now, so I get to relax for a little bit. Now I just have to figure out how — I think I’ve forgotten.

I may blow up a few things in Warcraft, or I may go hide away and read a book. Movies are out — all that’s playing in Morris right now is Wall-E. At any rate, I think I’ll drop offline for a few hours and do something that doesn’t involve deep thought and tapping away at a keyboard (unless, of course, my editor demands fast rewrites, which could happen). I’ll be leaving you all to your own wiles for a wee bit — consider this thread an open invitation to talk about your pleasant pastimes that do not involve SIWOTI syndrome.

It’s got almost everything!

How about a little extreme right wing paranoia to start your morning?

Global warming is the perfect excuse to do what the Left always wanted to do – to destroy faith (Christianity), the family and freedom. There is no area of our lives that will not be invaded through taxation, control, regulation or obliteration to save the earth.

Read the whole thing — global warming is the conspiracy that ties together abortion, taxes, communism, and our hatred of little children. If only it had mentioned evolution, it would have been perfect.

Also, it’s from a Canadian. It’s reassuring to see that the US doesn’t have a monopoly on loons. To be fair, though, the replies from other Canadians are scathing.

It’s a cracker, people

Good grief, but this is tedious. I’m still getting piles of email every day from people 1) begging me not to abuse a cracker because it is so sacred to them, piles of email telling me to 2) abuse a book because it is so sacred to Muslims (I’ve even been sent two copies of the Koran!), and of course, the 3) bizarre complaint that I’m a coward, afraid to commit sacrilege. You can all stop now. 1) Your personal sense of the sacred in a piece of bread dough is absurd to me and imposes on me no sense of obligation. 2) Since I now own one entirely superfluous copy of the Koran, it will meet the very same fate as the crackers. Thanks to all who have demanded that I treat that silly book with disrespect, I’ll have to treat both equally. 3) I have not rushed to be rude to a cracker because, well, it’s there, it’s ridiculous, and it’s not very important. I’ve been traveling, and I’ve come home to writing deadlines, and those get first priority. Heck, going into the kitchen right now and fixing myself a sandwich for lunch has higher priority. After I’ve cleared the deck of my work this week, then I might take a moment to casually demolish a sacred cow.

Now enough. You can all stop dunning me. Be patient, godless ones, and surrender to despair, O Ye Believers. And if this turns into another thousand comment thread, I shall be very, very cranky.

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