When we bought our house, it came with a disconnected, nonfunctional hot tub. It’s still here, sitting unused in our back yard, because having a mere Ph.D. in biology means that I don’t know how to fix it, and also, I don’t get paid enough to afford to have it fixed by a competent hot tub expert. And thus am I made to realize that I am a failure. I shouldn’t have wasted effort on that lowly science degree; instead, I should have learned how to install hot tubs.
Because hot tub experts are wizards, masters of all knowledge and the mysteries of space and time.
I have been reading the works of James Arjuna, International Spa Design Engineer, who is a real scientist. He said so.
I am a real scientist for over 47 years. I make my living producing functional equipment that always works as designed because I don’t use any pseudo science. I hate pseudo science religious crap in academia.
He says so frequently.
Please check out my science blog. It is based on over 47 years of using the scientific method to solve problems and to seek to find what is really true.
Here is where I do most of my recent research. I have read over 41,000 papers on biology, DNA, Evolution, genetics.
I don’t know which science blog to check out, though, since he didn’t provide a link. He has several!
- Hot Tubs And Spas Blog
- Education Literacy and Science
- Science, Religion, Politics What’s More Important?
- Evolution Science Clarity
41,000 papers is a lot. In 47 years, that’s 2 or 3 papers a day, which is about what I read. It’s hard work reading a science paper with comprehension, so his dedication to biology may be why his hot tub business has some bitter complaints, and why his brother thinks he’s a sleazy con artist. Mastery of all knowledge and the mysteries of space and time makes demands on one’s life; sacrifices must be made. This is another mark of my failure; I’m not guilty of bad business practices, and I haven’t alienated either of my brothers yet. I don’t think; maybe I’ll have to ask when I see them next month.
So I looked up Arjuna’s latest science article to learn wisdom and discover the deep secrets of the Hot Tub Masters. In this, he asserts that there is not and never has been a beneficial mutation. His chosen example? The lactose tolerance mutation, because while it may be beneficial, it couldn’t possibly have happened.
The most ridiculous of this is the lactose tolerance mutation. First of all making lactase is made in a gene that is 49,335 base pairs for just one of the THREE lactase genes. This is the most common gene found in lactose intolerance.
First rule of the Hot Tub Masters: Find a big number. Numbers are sciencey, and big ones are hard, and 49,335 sounds scary. How could it be? 49,355 whatevers must be impossible!
According to the article claiming that this was some great event creating this new gene. It turns out that it is only 2 base pares were changed to cause this gene to function. Where did the other totally designed 49332 BP come from that were aligned perfectly and just needed two base pares to change?
Second rule of the Hot Tub Masters: Find a small number. We must trivialize any accomplishment. Only 2 out of that intimidating 49,355? That can’t possibly matter. The scientists will splutter, “but single nucleotide changes can distort the whole shape of a molecule, or disrupt a biochemically active site; and in this case, the modification is to a cis regulatory element which modifies expression, not the sequence of the enzyme”, but you can ignore them, because of the obvious fact that 2 is a lot less than 49,355.
Third rule of the Hot Tub Masters: You are not bounded by any rules. Even though you’re making a strangely irrelevant argument from arithmetic, you can say that 49355 – 2 = 49332, and no one will care. Also, spelling is an oppressive tool of those pinheads in academia.
Fourth rule of the Hot Tub Masters: You can read
41,000 papers on biology, DNA, Evolution, genetics and still not understand basic biology, and that’s OK. The thousands of bases in a gene must be
aligned perfectly in your head, whatever that means, and never mind that that is not a rule in reality.
Hot Tub Masters are free spirits. Truth is whatever they say it is.
It was a pre-existing gene from ancient ancestors prior to this finding and they found a group where it was turned off and then a group where they drank milk where it was functioning. The two base pairs were not mutated from disease in the functioning gene and in the malfunctioning gene it was and is a disease.
Fifth rule of the Hot Tub Masters: Consistency be damned. You can simultaneously announce that there is no such thing as a beneficial mutation, and that groups without the mutation are
diseased (surprise, lactose intolerant individuals! You are afflicted with a disease!) and that groups that have the mutation are not diseased. And that it wasn’t a mutation anyway.
In the 2.5 million DNA studies there are no cases of any living or recently extinct (6000 yrs on human studies) showing even one verifiable beneficial mutation.
Not one of the PhD’s have been able to produce one. Therefore, there is no such thing as a beneficial mutation. It is fantasy.
But…but James! You’ve only read 41,000 of the 2.5 million studies!
And I am so confused. The Hot Tub Master plainly said that the 2 nucleotide variation was the difference between diseased and not diseased. Even in his own head it’s clearly beneficial to carry that trait.
We know that Evolutionists believe that “duplication” mutations are the “power behind evolution”. But even a base pair duplication causes disease or deformity because it destroys the original proteins construction with extra proteins that cannot be integrated.
Well, a single base pair duplication would be a frame shift mutation, so it certainly would mess up the structure of the protein. But we’re talking about segmental duplications, where a complete copy of the original gene is left intact and a duplicate is made elsewhere.
I don’t even understand what he’s talking about when he says a single base duplication creates
extra proteins that cannot be integrated. That makes no sense. It’s almost as if he has no understanding of molecular biology and genetics at all.
But that cannot be! He’s an International
Man of Mystery Spa Design Engineer!
They cannot be integrated because the HOX genes have to place them into the correct use and the HOX genes are master programmed for a specific master plan of the organism.
Then they cannot be recognized by the immune system and so the immune system takes the only messed up proteins and attacks them. Every mutation destroys the recognition of both the HOX to use them and the immune system to destroy them as foreign attack cells, that our immune system does not recognize.
I…what? I know a little bit about HOX genes; they don’t control every little thing, every gene in every cell. They set up domains with specific body plan identities in early development. Most genes don’t interact with HOX genes at all, so it’s a little peculiar to claim they limit everything — I’m beginning to think the Hot Tub Master memorized a few buzz words and phrases and is plastering them all over his cartoonish and wrong vision of how gene regulation works.
As for his immune system argument — does he know nothing about how adaptive immunity works? How self/non-self recognition is a product of selection?
James Arjuna is bringing discredit to the noble traditions of the Hot Tub Masters. I suspect that he is not a True Hot Tub Master™, and I’m going to have to look farther for a master of all knowledge and the mysteries of space and time. I also think my broken hot tub is going to continue to languish in my back yard, because if his knowledge of hot tubs is as sound as his knowledge of biology, I wouldn’t want him to come near it.
I know I sure can’t do anything about it. I know nothing about hot tubs. Nothing at all.