Over on NewGrounds, there’s a a short autobiographical game by Auntie Pixellante called Dys4ia. It’s a pixelly, Flash-based WarioWare-style game, played only with the arrow keys, chronicling the experiences of a trans woman in rectifying her own dysphoria.
I don’t want to spoil it overly much. It’s short, not difficult (except maybe emotionally), and well worth your time. Go play it.